Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EL263_RS10105 Genome accession   NZ_AP018938
Coordinates   1874874..1875176 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1869874..1880176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS10075 (SPAT_1908) rnpA 1870553..1870924 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EL263_RS12005 - 1870941..1871072 (-) 132 WP_000768904.1 hypothetical protein -
  EL263_RS10080 (SPAT_1909) - 1871073..1872263 (-) 1191 WP_000167766.1 acetate kinase -
  EL263_RS10085 (SPAT_1910) comYH 1872314..1873267 (-) 954 WP_050308921.1 class I SAM-dependent methyltransferase Machinery gene
  EL263_RS10090 - 1873328..1873922 (-) 595 Protein_1882 class I SAM-dependent methyltransferase -
  EL263_RS10095 (SPAT_1913) comGG/cglG 1874059..1874472 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL263_RS10100 (SPAT_1914) comGF/cglF 1874450..1874911 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL263_RS10105 (SPAT_1915) comGE/cglE 1874874..1875176 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL263_RS10110 (SPAT_1916) comGD/cglD 1875139..1875543 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL263_RS10115 (SPAT_1917) comGC/cglC 1875536..1875862 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  EL263_RS10120 (SPAT_1918) comGB/cglB 1875864..1876880 (-) 1017 WP_114880773.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL263_RS10125 (SPAT_1919) comGA/cglA/cilD 1876828..1877769 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  EL263_RS10130 (SPAT_1920) - 1877845..1878210 (-) 366 WP_000286415.1 DUF1033 family protein -
  EL263_RS10135 (SPAT_1921) - 1878361..1879419 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=71975 EL263_RS10105 WP_000413380.1 1874874..1875176(-) (comGE/cglE) [Streptococcus pneumoniae strain ATCC 49619]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=71975 EL263_RS10105 WP_000413380.1 1874874..1875176(-) (comGE/cglE) [Streptococcus pneumoniae strain ATCC 49619]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment