Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   EL263_RS10120 Genome accession   NZ_AP018938
Coordinates   1875864..1876880 (-) Length   338 a.a.
NCBI ID   WP_114880773.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1870864..1881880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS12005 - 1870941..1871072 (-) 132 WP_000768904.1 hypothetical protein -
  EL263_RS10080 (SPAT_1909) - 1871073..1872263 (-) 1191 WP_000167766.1 acetate kinase -
  EL263_RS10085 (SPAT_1910) comYH 1872314..1873267 (-) 954 WP_050308921.1 class I SAM-dependent methyltransferase Machinery gene
  EL263_RS10090 - 1873328..1873922 (-) 595 Protein_1882 class I SAM-dependent methyltransferase -
  EL263_RS10095 (SPAT_1913) comGG/cglG 1874059..1874472 (-) 414 WP_050102600.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL263_RS10100 (SPAT_1914) comGF/cglF 1874450..1874911 (-) 462 WP_000250544.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL263_RS10105 (SPAT_1915) comGE/cglE 1874874..1875176 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL263_RS10110 (SPAT_1916) comGD/cglD 1875139..1875543 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL263_RS10115 (SPAT_1917) comGC/cglC 1875536..1875862 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  EL263_RS10120 (SPAT_1918) comGB/cglB 1875864..1876880 (-) 1017 WP_114880773.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL263_RS10125 (SPAT_1919) comGA/cglA/cilD 1876828..1877769 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  EL263_RS10130 (SPAT_1920) - 1877845..1878210 (-) 366 WP_000286415.1 DUF1033 family protein -
  EL263_RS10135 (SPAT_1921) - 1878361..1879419 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EL263_RS10140 (SPAT_1922) nagA 1879582..1880733 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38548.65 Da        Isoelectric Point: 9.8287

>NTDB_id=71978 EL263_RS10120 WP_114880773.1 1875864..1876880(-) (comGB/cglB) [Streptococcus pneumoniae strain ATCC 49619]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETITFLDRSALLDKQCVIQMRAGLSQGKSFSEMMESLGFSSTI
ITQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVRTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=71978 EL263_RS10120 WP_114880773.1 1875864..1876880(-) (comGB/cglB) [Streptococcus pneumoniae strain ATCC 49619]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCACCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGATCCAGATGCGTGCGGGCTTGTCTCAAGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATTTTCAAGCACCATT
ATCACTCAGTTATCCCTAGCTGAAGTTCATGGAAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCGGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

97.337

100

0.973
  comGB/cglB Streptococcus pneumoniae D39

97.337

100

0.973
  comGB/cglB Streptococcus pneumoniae R6

97.337

100

0.973
  comGB/cglB Streptococcus pneumoniae TIGR4

97.337

100

0.973
  comGB/cglB Streptococcus mitis SK321

94.083

100

0.941
  comGB/cglB Streptococcus mitis NCTC 12261

93.787

100

0.938
  comYB Streptococcus gordonii str. Challis substr. CH1

71.131

99.408

0.707
  comYB Streptococcus mutans UA140

57.862

94.083

0.544
  comYB Streptococcus mutans UA159

57.862

94.083

0.544
  comGB Lactococcus lactis subsp. cremoris KW2

51.198

98.817

0.506

Multiple sequence alignment