Detailed information NTG0719035

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: NWO26_RS06440
• Genome accession: NZ_CP102797
• Coordinates: 1263587..1263913 (-)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain ST057-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1258587..1268913

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWO26_RS06395	-	1258852..1259190 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
NWO26_RS06400	-	1259234..1259509 (-)	276	WP_011681681.1	hypothetical protein	-
NWO26_RS06405	-	1259521..1259719 (-)	199	Protein_1263	helix-turn-helix transcriptional regulator	-
NWO26_RS06410	-	1259968..1261161 (-)	1194	WP_014608740.1	acetate kinase	-
NWO26_RS06415	comYH	1261217..1262173 (-)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
NWO26_RS06420	comGG	1262218..1262535 (-)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
NWO26_RS06425	comYF	1262513..1262950 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
NWO26_RS06430	comGE	1262934..1263227 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
NWO26_RS06435	comYD	1263199..1263627 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
NWO26_RS06440	comYC	1263587..1263913 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
NWO26_RS06445	comYB	1263910..1265010 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
NWO26_RS06450	comGA/cglA/cilD	1264892..1265833 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
NWO26_RS06455	-	1265914..1266276 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=719035 NWO26_RS06440 WP_002946126.1 1263587..1263913(-) (comYC) [Streptococcus thermophilus strain ST057-1]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=719035 NWO26_RS06440 WP_002946126.1 1263587..1263913(-) (comYC) [Streptococcus thermophilus strain ST057-1]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361