Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   MOP79_RS10200 Genome accession   NZ_CP102583
Coordinates   1997896..1998375 (-) Length   159 a.a.
NCBI ID   WP_000588897.1    Uniprot ID   Q9R2W8
Organism   Streptococcus pneumoniae strain D39Mega17545     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1992896..2003375
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MOP79_RS10170 phtD 1995420..1996751 (-) 1332 Protein_2015 pneumococcal histidine triad protein PhtD -
  MOP79_RS10190 - 1997241..1997528 (-) 288 Protein_2016 ISL3 family transposase -
  MOP79_RS10200 comX/comX2 1997896..1998375 (-) 480 WP_000588897.1 sigma-70 family RNA polymerase sigma factor Regulator
  MOP79_RS10205 - 1998502..1999254 (-) 753 Protein_2018 dihydrodipicolinate synthase family protein -
  MOP79_RS10250 - 1999968..2000578 (-) 611 Protein_2019 transposase -
  MOP79_RS10255 - 2000578..2001150 (+) 573 Protein_2020 N-acetylmannosamine-6-phosphate 2-epimerase -
  MOP79_RS10260 - 2001151..2001674 (-) 524 Protein_2021 transposase -
  MOP79_RS10265 - 2001676..2002100 (+) 425 Protein_2022 transposase family protein -
  MOP79_RS10270 - 2002082..2002408 (-) 327 Protein_2023 transposase -
  MOP79_RS10625 - 2002442..2002516 (-) 75 Protein_2024 IS3 family transposase -
  MOP79_RS10275 - 2002502..2002933 (+) 432 Protein_2025 SSURE domain-containing protein -
  MOP79_RS10280 - 2002939..2003145 (-) 207 Protein_2026 IS630 transposase-related protein -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19873.52 Da        Isoelectric Point: 7.3797

>NTDB_id=717906 MOP79_RS10200 WP_000588897.1 1997896..1998375(-) (comX/comX2) [Streptococcus pneumoniae strain D39Mega17545]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=717906 MOP79_RS10200 WP_000588897.1 1997896..1998375(-) (comX/comX2) [Streptococcus pneumoniae strain D39Mega17545]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9R2W8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

100

100

1
  comX/comX1 Streptococcus pneumoniae Rx1

100

100

1
  comX/comX2 Streptococcus pneumoniae D39

100

100

1
  comX/comX1 Streptococcus pneumoniae D39

100

100

1
  comX/comX2 Streptococcus pneumoniae R6

100

100

1
  comX/comX1 Streptococcus pneumoniae R6

100

100

1
  comX/comX2 Streptococcus pneumoniae TIGR4

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae TIGR4

99.371

100

0.994
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

92.453

100

0.925
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

92.453

100

0.925
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

90.566

100

0.906
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

89.241

99.371

0.887
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comX/sigX Streptococcus mutans UA159

46

94.34

0.434
  comX/sigX Streptococcus suis isolate S10

45.695

94.969

0.434
  comX/sigX Streptococcus suis D9

45.695

94.969

0.434
  comX/sigX Streptococcus suis P1/7

45.695

94.969

0.434
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

94.34

0.377