Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   NQZ84_RS00740 Genome accession   NZ_CP102094
Coordinates   120671..121621 (+) Length   316 a.a.
NCBI ID   WP_044769405.1    Uniprot ID   -
Organism   Streptococcus suis strain 12RC1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115671..126621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS00730 (NQZ84_00730) - 119235..119600 (+) 366 WP_002936568.1 DUF1033 family protein -
  NQZ84_RS00735 (NQZ84_00735) - 119635..120585 (-) 951 WP_257049510.1 S66 family peptidase -
  NQZ84_RS00740 (NQZ84_00740) comYA 120671..121621 (+) 951 WP_044769405.1 competence type IV pilus ATPase ComGA Machinery gene
  NQZ84_RS00745 (NQZ84_00745) comYB 121533..122570 (+) 1038 WP_044769407.1 competence type IV pilus assembly protein ComGB Machinery gene
  NQZ84_RS00750 (NQZ84_00750) comYC 122572..122853 (+) 282 WP_044683533.1 competence type IV pilus major pilin ComGC Machinery gene
  NQZ84_RS00755 (NQZ84_00755) comGD 122834..123241 (+) 408 WP_044685579.1 competence type IV pilus minor pilin ComGD -
  NQZ84_RS00760 (NQZ84_00760) comYE 123213..123506 (+) 294 WP_024413203.1 competence type IV pilus minor pilin ComGE Machinery gene
  NQZ84_RS00765 (NQZ84_00765) comGF/cglF 123493..123927 (+) 435 WP_024389483.1 competence type IV pilus minor pilin ComGF Machinery gene
  NQZ84_RS00770 (NQZ84_00770) comGG 123905..124315 (+) 411 WP_024389482.1 competence type IV pilus minor pilin ComGG -
  NQZ84_RS00775 (NQZ84_00775) comYH 124372..125325 (+) 954 WP_044753390.1 class I SAM-dependent methyltransferase Machinery gene
  NQZ84_RS00780 (NQZ84_00780) - 125375..126562 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35435.33 Da        Isoelectric Point: 6.1790

>NTDB_id=714281 NQZ84_RS00740 WP_044769405.1 120671..121621(+) (comYA) [Streptococcus suis strain 12RC1]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGKISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSANQWNEQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=714281 NQZ84_RS00740 WP_044769405.1 120671..121621(+) (comYA) [Streptococcus suis strain 12RC1]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGATATTTATCTGGTTCCTCGTGG
TCAAGGCTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGTGGAAAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCTAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCTAC
CTACGATAATCTGATTAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAGATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACAGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCTCGTATGTTGGAATTGGGTGTCAGTCCTGAAGAGCTAAATAATGCCCTTCAAGGTATTGCCTATCAACGATTGATTGG
GGGAGGAGGTGTGGTAGATTTTGCAAAAGGAAATTACCAAAACCATTCCGCAAACCAGTGGAATGAACAAATTGATCGGC
TTTTTGCAGCAGGACATATCAGTCTTCGTCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364