Detailed information NTG0712334

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: NOV99_RS10185
• Genome accession: NZ_CP101844
• Coordinates: 2078125..2078406 (-)
• Length: 93 a.a.
• NCBI ID: WP_002936550.1
• Uniprot ID: G7SD61
• Organism: Streptococcus suis strain 2018WUSS151
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2073125..2083406

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NOV99_RS10150 (NOV99_10150)	-	2073550..2074101 (-)	552	WP_014636756.1	folate family ECF transporter S component	-
NOV99_RS10155 (NOV99_10155)	-	2074416..2075603 (-)	1188	WP_002936543.1	acetate kinase	-
NOV99_RS10160 (NOV99_10160)	comYH	2075653..2076606 (-)	954	WP_002936545.1	class I SAM-dependent methyltransferase	Machinery gene
NOV99_RS10165 (NOV99_10165)	comGG	2076663..2077073 (-)	411	WP_002936546.1	competence type IV pilus minor pilin ComGG	-
NOV99_RS10170 (NOV99_10170)	comGF/cglF	2077051..2077485 (-)	435	WP_002936547.1	competence type IV pilus minor pilin ComGF	Machinery gene
NOV99_RS10175 (NOV99_10175)	comYE	2077472..2077765 (-)	294	WP_002936548.1	competence type IV pilus minor pilin ComGE	Machinery gene
NOV99_RS10180 (NOV99_10180)	comGD	2077737..2078144 (-)	408	WP_014636753.1	competence type IV pilus minor pilin ComGD	-
NOV99_RS10185 (NOV99_10185)	comYC	2078125..2078406 (-)	282	WP_002936550.1	competence type IV pilus major pilin ComGC	Machinery gene
NOV99_RS10190 (NOV99_10190)	comYB	2078408..2079445 (-)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
NOV99_RS10195 (NOV99_10195)	comYA	2079357..2080307 (-)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
NOV99_RS10200 (NOV99_10200)	-	2080393..2081343 (+)	951	WP_002936565.1	S66 peptidase family protein	-
NOV99_RS10205 (NOV99_10205)	-	2081378..2081743 (-)	366	WP_002936568.1	DUF1033 family protein	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10452.31 Da
• Isoelectric Point: 5.1667

>NTDB_id=712334 NOV99_RS10185 WP_002936550.1 2078125..2078406(-) (comYC) [Streptococcus suis strain 2018WUSS151]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSKQKDAVQEKGNAAVVKVVESQMELYELEHDEEATVEDLQQAGYI
TEKQAKQYATAKK

Nucleotide

• Length: 282 bp

>NTDB_id=712334 NOV99_RS10185 WP_002936550.1 2078125..2078406(-) (comYC) [Streptococcus suis strain 2018WUSS151]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCTTATTTGTGCCAAATTTGAGCAAACAAAAGGATGCTGTTCAAGAGAAAGGAAATGCTGCCGTTGTCAAAGTAG
TGGAGAGTCAGATGGAGCTCTACGAATTGGAACATGACGAGGAAGCAACGGTGGAGGATTTGCAACAGGCAGGTTATATT
ACTGAAAAACAAGCAAAACAGTATGCTACGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: G7SD61

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	92.473	100	0.925
comGC/cglC	Streptococcus pneumoniae TIGR4	68.182	94.624	0.645
comGC/cglC	Streptococcus pneumoniae Rx1	68.182	94.624	0.645
comGC/cglC	Streptococcus pneumoniae D39	68.182	94.624	0.645
comGC/cglC	Streptococcus pneumoniae R6	68.182	94.624	0.645
comGC/cglC	Streptococcus mitis SK321	69.412	91.398	0.634
comGC/cglC	Streptococcus mitis NCTC 12261	69.412	91.398	0.634
comYC	Streptococcus gordonii str. Challis substr. CH1	65.169	95.699	0.624
comYC	Streptococcus mutans UA140	61.364	94.624	0.581
comYC	Streptococcus mutans UA159	61.364	94.624	0.581
comGC	Lactococcus lactis subsp. cremoris KW2	59.091	94.624	0.559
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	46.667	80.645	0.376