Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   NOV99_RS10190 Genome accession   NZ_CP101844
Coordinates   2078408..2079445 (-) Length   345 a.a.
NCBI ID   WP_255195823.1    Uniprot ID   -
Organism   Streptococcus suis strain 2018WUSS151     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2073408..2084445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NOV99_RS10150 (NOV99_10150) - 2073550..2074101 (-) 552 WP_014636756.1 folate family ECF transporter S component -
  NOV99_RS10155 (NOV99_10155) - 2074416..2075603 (-) 1188 WP_002936543.1 acetate kinase -
  NOV99_RS10160 (NOV99_10160) comYH 2075653..2076606 (-) 954 WP_002936545.1 class I SAM-dependent methyltransferase Machinery gene
  NOV99_RS10165 (NOV99_10165) comGG 2076663..2077073 (-) 411 WP_002936546.1 competence type IV pilus minor pilin ComGG -
  NOV99_RS10170 (NOV99_10170) comGF/cglF 2077051..2077485 (-) 435 WP_002936547.1 competence type IV pilus minor pilin ComGF Machinery gene
  NOV99_RS10175 (NOV99_10175) comYE 2077472..2077765 (-) 294 WP_002936548.1 competence type IV pilus minor pilin ComGE Machinery gene
  NOV99_RS10180 (NOV99_10180) comGD 2077737..2078144 (-) 408 WP_014636753.1 competence type IV pilus minor pilin ComGD -
  NOV99_RS10185 (NOV99_10185) comYC 2078125..2078406 (-) 282 WP_002936550.1 competence type IV pilus major pilin ComGC Machinery gene
  NOV99_RS10190 (NOV99_10190) comYB 2078408..2079445 (-) 1038 WP_255195823.1 competence type IV pilus assembly protein ComGB Machinery gene
  NOV99_RS10195 (NOV99_10195) comYA 2079357..2080307 (-) 951 WP_002936562.1 competence type IV pilus ATPase ComGA Machinery gene
  NOV99_RS10200 (NOV99_10200) - 2080393..2081343 (+) 951 WP_002936565.1 S66 peptidase family protein -
  NOV99_RS10205 (NOV99_10205) - 2081378..2081743 (-) 366 WP_002936568.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39014.08 Da        Isoelectric Point: 9.4805

>NTDB_id=712335 NOV99_RS10190 WP_255195823.1 2078408..2079445(-) (comYB) [Streptococcus suis strain 2018WUSS151]
MRKLIAFLQQDISVLGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADLYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLFLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVAVLAGMVWFRKTNKIKAFSRLAALPFFGKLIQIYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=712335 NOV99_RS10190 WP_255195823.1 2078408..2079445(-) (comYB) [Streptococcus suis strain 2018WUSS151]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCTCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCGAGTTTACTG
GCAGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TGGGTTTTCTGTTCTTGATTATGCTAGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCTGCGACCATG
CTAATTAACCATCTGCCGACTATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTGGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATCAAGGCATTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAATCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGAAGTTTGATTGGGCAAGGCTTGGACCTGCCACAGATTGTGGGCTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGGCAGAGCTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGTTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis SK321

60.119

97.391

0.586
  comYB Streptococcus mutans UA140

58.944

98.841

0.583
  comYB Streptococcus mutans UA159

58.944

98.841

0.583
  comGB/cglB Streptococcus mitis NCTC 12261

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae Rx1

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae D39

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae R6

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae TIGR4

59.104

97.101

0.574
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.681

0.496