Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   NLY76_RS00740 Genome accession   NZ_CP100430
Coordinates   120347..121297 (+) Length   316 a.a.
NCBI ID   WP_044770156.1    Uniprot ID   -
Organism   Streptococcus suis strain LSS42     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115347..126297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS00730 (NLY76_00730) - 118911..119276 (+) 366 WP_024386552.1 DUF1033 family protein -
  NLY76_RS00735 (NLY76_00735) - 119311..120261 (-) 951 WP_044770155.1 S66 peptidase family protein -
  NLY76_RS00740 (NLY76_00740) comYA 120347..121297 (+) 951 WP_044770156.1 competence type IV pilus ATPase ComGA Machinery gene
  NLY76_RS00745 (NLY76_00745) comYB 121209..122246 (+) 1038 WP_044770157.1 competence type IV pilus assembly protein ComGB Machinery gene
  NLY76_RS00750 (NLY76_00750) comYC 122248..122529 (+) 282 WP_044770158.1 competence type IV pilus major pilin ComGC Machinery gene
  NLY76_RS00755 (NLY76_00755) comGD 122510..122917 (+) 408 WP_044770160.1 competence type IV pilus minor pilin ComGD -
  NLY76_RS00760 (NLY76_00760) comYE 122889..123182 (+) 294 WP_024401507.1 competence type IV pilus minor pilin ComGE Machinery gene
  NLY76_RS00765 (NLY76_00765) comGF/cglF 123169..123603 (+) 435 WP_052833555.1 competence type IV pilus minor pilin ComGF Machinery gene
  NLY76_RS00770 (NLY76_00770) comGG 123581..123991 (+) 411 WP_009909099.1 competence type IV pilus minor pilin ComGG -
  NLY76_RS00775 (NLY76_00775) comYH 124048..125001 (+) 954 WP_014637318.1 class I SAM-dependent methyltransferase Machinery gene
  NLY76_RS00780 (NLY76_00780) - 125051..126238 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35479.34 Da        Isoelectric Point: 5.4799

>NTDB_id=705189 NLY76_RS00740 WP_044770156.1 120347..121297(+) (comYA) [Streptococcus suis strain LSS42]
MIQEKARKMIEEAVADRVSDIYLVPRGQDYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADKWNEQIDRLFAAGHISLRQAETEKIALGAPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=705189 NLY76_RS00740 WP_044770156.1 120347..121297(+) (comYA) [Streptococcus suis strain LSS42]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGTGG
TCAGGACTACCAAGTCTACCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGATTAAATGTTGGTGAAAAACGCCGTAGTCAGCAGGGTTCCTGTGATTATGAT
TATGGCAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGTAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTTAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACTATCGAGGATCCTGTCGAGATCAAGCAGGAGGATATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGGCCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACGG
CGCGGGCGGTCATCAGGGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGCCCTGAAGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGCTTGATTGG
GGGAGGAGGTGTAGTGGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACAAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

98.418

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.943

100

0.541
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361