Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   NLY76_RS00745 Genome accession   NZ_CP100430
Coordinates   121209..122246 (+) Length   345 a.a.
NCBI ID   WP_044770157.1    Uniprot ID   -
Organism   Streptococcus suis strain LSS42     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 116209..127246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS00730 (NLY76_00730) - 118911..119276 (+) 366 WP_024386552.1 DUF1033 family protein -
  NLY76_RS00735 (NLY76_00735) - 119311..120261 (-) 951 WP_044770155.1 S66 peptidase family protein -
  NLY76_RS00740 (NLY76_00740) comYA 120347..121297 (+) 951 WP_044770156.1 competence type IV pilus ATPase ComGA Machinery gene
  NLY76_RS00745 (NLY76_00745) comYB 121209..122246 (+) 1038 WP_044770157.1 competence type IV pilus assembly protein ComGB Machinery gene
  NLY76_RS00750 (NLY76_00750) comYC 122248..122529 (+) 282 WP_044770158.1 competence type IV pilus major pilin ComGC Machinery gene
  NLY76_RS00755 (NLY76_00755) comGD 122510..122917 (+) 408 WP_044770160.1 competence type IV pilus minor pilin ComGD -
  NLY76_RS00760 (NLY76_00760) comYE 122889..123182 (+) 294 WP_024401507.1 competence type IV pilus minor pilin ComGE Machinery gene
  NLY76_RS00765 (NLY76_00765) comGF/cglF 123169..123603 (+) 435 WP_052833555.1 competence type IV pilus minor pilin ComGF Machinery gene
  NLY76_RS00770 (NLY76_00770) comGG 123581..123991 (+) 411 WP_009909099.1 competence type IV pilus minor pilin ComGG -
  NLY76_RS00775 (NLY76_00775) comYH 124048..125001 (+) 954 WP_014637318.1 class I SAM-dependent methyltransferase Machinery gene
  NLY76_RS00780 (NLY76_00780) - 125051..126238 (+) 1188 WP_014637319.1 acetate kinase -
  NLY76_RS00785 (NLY76_00785) - 126553..127104 (+) 552 WP_044674513.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39017.96 Da        Isoelectric Point: 9.3127

>NTDB_id=705190 NLY76_RS00745 WP_044770157.1 121209..122246(+) (comYB) [Streptococcus suis strain LSS42]
MNKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLCGLSLVAVMSSLVWFRKTNKIKAFSRLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLFNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=705190 NLY76_RS00745 WP_044770157.1 121209..122246(+) (comYB) [Streptococcus suis strain LSS42]
ATGAACAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCG
CCAGCGTAAGGTTATTGAACTGTTTAACAATCTCTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GTAGCCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCGAGTTTACTG
GCAGATTTGCGATTCTCAGACGCGGTTGTAACACAGGTAGCTCTGGCAGAGGTCCATGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATATTGC
TTGGTTTTCTGCTTTTGATTATGCTAGGTTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACCGTG
CTAATTAACCATCTGCCGACCATCTTCTTGTCCCTTTGTGGTCTGAGTTTAGTGGCTGTCATGTCTAGTCTGGTTTGGTT
TCGTAAAACAAACAAAATCAAGGCATTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCACAGATTGTGGGCTTGATGCAGGAG
CAGCAATCGCAACTCTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTTCAATGGTCAGAGCTTTCACGAACACAT
CAAGACCTACGCCTTTTTCAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGC
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

62.865

99.13

0.623
  comGB/cglB Streptococcus mitis NCTC 12261

60.299

97.101

0.586
  comGB/cglB Streptococcus mitis SK321

60

97.101

0.583
  comYB Streptococcus mutans UA140

58.944

98.841

0.583
  comYB Streptococcus mutans UA159

58.944

98.841

0.583
  comGB/cglB Streptococcus pneumoniae Rx1

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae D39

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae R6

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae TIGR4

59.701

97.101

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.681

0.496