Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   STO1_RS08765 Genome accession   NZ_AP018338
Coordinates   1712862..1713185 (-) Length   107 a.a.
NCBI ID   WP_000735798.1    Uniprot ID   A0A1X1HB54
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1707862..1718185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS08725 (STO1_016610) rnpA 1707988..1708359 (-) 372 WP_000748120.1 ribonuclease P protein component -
  STO1_RS08730 (STO1_016620) - 1708509..1709699 (-) 1191 WP_000167800.1 acetate kinase -
  STO1_RS08735 (STO1_016630) comYH 1709750..1710703 (-) 954 WP_084917154.1 class I SAM-dependent methyltransferase Machinery gene
  STO1_RS08740 (STO1_016640) - 1710762..1711352 (-) 591 WP_096422845.1 class I SAM-dependent methyltransferase -
  STO1_RS08745 (STO1_016650) comGG/cglG 1711385..1711798 (-) 414 WP_096422847.1 competence type IV pilus minor pilin ComGG Machinery gene
  STO1_RS08750 (STO1_016660) comGF/cglF 1711776..1712237 (-) 462 WP_000250700.1 competence type IV pilus minor pilin ComGF Machinery gene
  STO1_RS08755 (STO1_016670) comGE/cglE 1712200..1712502 (-) 303 WP_000413383.1 competence type IV pilus minor pilin ComGE Machinery gene
  STO1_RS08760 (STO1_016680) comGD/cglD 1712465..1712899 (-) 435 WP_172843654.1 competence type IV pilus minor pilin ComGD Machinery gene
  STO1_RS08765 (STO1_016690) comGC/cglC 1712862..1713185 (-) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  STO1_RS08770 comGB/cglB 1713187..1714203 (-) 1017 WP_162138308.1 competence type IV pilus assembly protein ComGB Machinery gene
  STO1_RS08775 (STO1_016710) comGA/cglA/cilD 1714151..1715092 (-) 942 WP_061428665.1 competence type IV pilus ATPase ComGA Machinery gene
  STO1_RS08780 (STO1_016720) - 1715161..1715526 (-) 366 WP_000286399.1 DUF1033 family protein -
  STO1_RS08785 (STO1_016730) nagA 1715679..1716830 (-) 1152 WP_096422851.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 11891.03 Da        Isoelectric Point: 10.1883

>NTDB_id=69091 STO1_RS08765 WP_000735798.1 1712862..1713185(-) (comGC/cglC) [Streptococcus oralis subsp. tigurinus strain osk_001]
MKKLMTNLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYRLDKNDDASLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=69091 STO1_RS08765 WP_000735798.1 1712862..1713185(-) (comGC/cglC) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGAAAAAACTCATGACAAATTTAAAAAAAGCCAAGGTTAAAGCTTTCACTTTGGTAGAAATGTTAGTCGTCTTGCTTAT
CATCAGCGTACTCCTCTTGCTCTTTGTGCCCAATTTGACCAAGCAAAAGGATGCCGTAGATGATAAAGGAAAAGCTGCTG
TTGTCAAGGTTGTGGAAAGCCAGGCAGAACTCTATCGTTTGGACAAAAATGATGACGCCAGCCTCAGCAAATTACAAGCG
GACGGTCGTATCACAGCTGAGCAAGCCAAAGCTTATAAAGACTACCATGCAAAACAAAAAACAAGTCAAACTGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1HB54

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

91.589

100

0.916
  comGC/cglC Streptococcus mitis SK321

88.889

92.523

0.822
  comGC/cglC Streptococcus pneumoniae R6

86.869

92.523

0.804
  comGC/cglC Streptococcus pneumoniae Rx1

86.869

92.523

0.804
  comGC/cglC Streptococcus pneumoniae D39

86.869

92.523

0.804
  comGC/cglC Streptococcus pneumoniae TIGR4

85.859

92.523

0.794
  comYC Streptococcus gordonii str. Challis substr. CH1

67.619

98.131

0.664
  comYC Streptococcus mutans UA140

70.103

90.654

0.636
  comYC Streptococcus mutans UA159

70.103

90.654

0.636
  comGC Lactococcus lactis subsp. cremoris KW2

57.426

94.393

0.542
  comYC Streptococcus suis isolate S10

65.909

82.243

0.542

Multiple sequence alignment