Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   STO1_RS08770 Genome accession   NZ_AP018338
Coordinates   1713187..1714203 (-) Length   338 a.a.
NCBI ID   WP_162138308.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1708187..1719203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS08730 (STO1_016620) - 1708509..1709699 (-) 1191 WP_000167800.1 acetate kinase -
  STO1_RS08735 (STO1_016630) comYH 1709750..1710703 (-) 954 WP_084917154.1 class I SAM-dependent methyltransferase Machinery gene
  STO1_RS08740 (STO1_016640) - 1710762..1711352 (-) 591 WP_096422845.1 class I SAM-dependent methyltransferase -
  STO1_RS08745 (STO1_016650) comGG/cglG 1711385..1711798 (-) 414 WP_096422847.1 competence type IV pilus minor pilin ComGG Machinery gene
  STO1_RS08750 (STO1_016660) comGF/cglF 1711776..1712237 (-) 462 WP_000250700.1 competence type IV pilus minor pilin ComGF Machinery gene
  STO1_RS08755 (STO1_016670) comGE/cglE 1712200..1712502 (-) 303 WP_000413383.1 competence type IV pilus minor pilin ComGE Machinery gene
  STO1_RS08760 (STO1_016680) comGD/cglD 1712465..1712899 (-) 435 WP_172843654.1 competence type IV pilus minor pilin ComGD Machinery gene
  STO1_RS08765 (STO1_016690) comGC/cglC 1712862..1713185 (-) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  STO1_RS08770 comGB/cglB 1713187..1714203 (-) 1017 WP_162138308.1 competence type IV pilus assembly protein ComGB Machinery gene
  STO1_RS08775 (STO1_016710) comGA/cglA/cilD 1714151..1715092 (-) 942 WP_061428665.1 competence type IV pilus ATPase ComGA Machinery gene
  STO1_RS08780 (STO1_016720) - 1715161..1715526 (-) 366 WP_000286399.1 DUF1033 family protein -
  STO1_RS08785 (STO1_016730) nagA 1715679..1716830 (-) 1152 WP_096422851.1 N-acetylglucosamine-6-phosphate deacetylase -
  STO1_RS08790 (STO1_016740) - 1716971..1718788 (-) 1818 WP_096422853.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38560.68 Da        Isoelectric Point: 9.6717

>NTDB_id=69092 STO1_RS08770 WP_162138308.1 1713187..1714203(-) (comGB/cglB) [Streptococcus oralis subsp. tigurinus strain osk_001]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVTQMHQGLSQGKSFSEMMESLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMKEQGSQLFKEI
GQDLSQALQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=69092 STO1_RS08770 WP_162138308.1 1713187..1714203(-) (comGB/cglB) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCCTGTTTAA
CAATCTCTTCTCCAGTGGTTTTCATTTGGTGGAAATTATTTCTTTCTTGGGTAGAAGTGCTTTGTTAGAAAAAGACTATG
TGACACAGATGCACCAAGGACTGTCTCAGGGAAAATCTTTCTCAGAAATGATGGAGAGTTTAGGGTTTTCAAGTGCCATT
GTGACTCAGCTATCCCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATCGAAGTAGCAACCTATCCTTTGATTTTGCTGGGATTTCTCCTGCTAATCATGTTGG
GGCTCAGGAATTATTTGCTCCCCCAACTGGACAGTAGCAATATCGCCACTCAAATCATCGGCAATCTGCCACAAATCTTT
CTGGGACTAGTGTTGGTTTGCTCTCTGTCTCTACTTTTAGCTCTCACTTTTTACAAAAGAAGTTCCAAGATGCGGGTCTT
CTCGATGTTAGCGCGGATTCCCTTTCTAGGAATCTTTGTCCAGACTTATCTGACAGCTTATTATGCGCGTGAATGGGGCA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATCATGAAGGAACAAGGTTCCCAACTCTTTAAAGAAATC
GGTCAAGATTTGTCTCAAGCCCTGCAAAATGGCCGTGAATTTTCTCAAACCATAGCGACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATCGAGTATGGAGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAACTTAGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

94.083

100

0.941
  comGB/cglB Streptococcus mitis NCTC 12261

93.195

100

0.932
  comGB/cglB Streptococcus pneumoniae Rx1

91.42

100

0.914
  comGB/cglB Streptococcus pneumoniae D39

91.42

100

0.914
  comGB/cglB Streptococcus pneumoniae R6

91.42

100

0.914
  comGB/cglB Streptococcus pneumoniae TIGR4

91.42

100

0.914
  comYB Streptococcus gordonii str. Challis substr. CH1

73.512

99.408

0.731
  comYB Streptococcus mutans UA140

58.934

94.379

0.556
  comYB Streptococcus mutans UA159

58.934

94.379

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

52.663

100

0.527

Multiple sequence alignment