Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   M8286_RS00730 Genome accession   NZ_CP097577
Coordinates   119127..120077 (+) Length   316 a.a.
NCBI ID   WP_275601167.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 114127..125077
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS00720 (M8286_00715) - 117689..118063 (+) 375 WP_024385120.1 DUF1033 family protein -
  M8286_RS00725 (M8286_00720) - 118091..119041 (-) 951 WP_275601166.1 S66 peptidase family protein -
  M8286_RS00730 (M8286_00725) comYA 119127..120077 (+) 951 WP_275601167.1 competence type IV pilus ATPase ComGA Machinery gene
  M8286_RS00735 (M8286_00730) comYB 119989..121026 (+) 1038 WP_358639410.1 competence type IV pilus assembly protein ComGB Machinery gene
  M8286_RS00740 (M8286_00735) comYC 121028..121309 (+) 282 WP_275601168.1 competence type IV pilus major pilin ComGC Machinery gene
  M8286_RS00745 (M8286_00740) comGD 121290..121697 (+) 408 WP_275601169.1 competence type IV pilus minor pilin ComGD -
  M8286_RS00750 (M8286_00745) comYE 121669..121962 (+) 294 WP_275601170.1 competence type IV pilus minor pilin ComGE Machinery gene
  M8286_RS00755 (M8286_00750) comGF/cglF 121949..122383 (+) 435 WP_275601171.1 competence type IV pilus minor pilin ComGF Machinery gene
  M8286_RS00760 (M8286_00755) comGG 122361..122879 (+) 519 WP_275601172.1 competence type IV pilus minor pilin ComGG -
  M8286_RS00765 (M8286_00760) comYH 122929..123882 (+) 954 WP_275601173.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35409.31 Da        Isoelectric Point: 5.6938

>NTDB_id=690312 M8286_RS00730 WP_275601167.1 119127..120077(+) (comYA) [Streptococcus suis strain 3112]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDMAEEEVIAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=690312 M8286_RS00730 WP_275601167.1 119127..120077(+) (comYA) [Streptococcus suis strain 3112]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTTAGTGACATTTATCTGGTTCCTCGTGG
TCAGGGCTACCAAGTCTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACATGGCTGAGGAAGAAGTAATAGCCA
TCATCAGTCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGTCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGTGGAGAGATTTCACTTCGCTTGTCAACTGTCGGAGATTATCGTGGTAAGGAAAGTCTGGTCATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCAGCTGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAGCTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTAATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAGATTCGGGATGCGGAAACTG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAC
GCCCGTATGTTAGAACTAGGTGTCAGCCCTGAGGAGTTAAACAATGCCCTTCAAGGGATTGCCTATCAACGTTTGATTGG
GGGAGGAGGTGTAGTAGATTTTGCAAAAGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGTTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535