Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   M8286_RS00735 Genome accession   NZ_CP097577
Coordinates   119989..121026 (+) Length   345 a.a.
NCBI ID   WP_358639410.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 114989..126026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS00720 (M8286_00715) - 117689..118063 (+) 375 WP_024385120.1 DUF1033 family protein -
  M8286_RS00725 (M8286_00720) - 118091..119041 (-) 951 WP_275601166.1 S66 peptidase family protein -
  M8286_RS00730 (M8286_00725) comYA 119127..120077 (+) 951 WP_275601167.1 competence type IV pilus ATPase ComGA Machinery gene
  M8286_RS00735 (M8286_00730) comYB 119989..121026 (+) 1038 WP_358639410.1 competence type IV pilus assembly protein ComGB Machinery gene
  M8286_RS00740 (M8286_00735) comYC 121028..121309 (+) 282 WP_275601168.1 competence type IV pilus major pilin ComGC Machinery gene
  M8286_RS00745 (M8286_00740) comGD 121290..121697 (+) 408 WP_275601169.1 competence type IV pilus minor pilin ComGD -
  M8286_RS00750 (M8286_00745) comYE 121669..121962 (+) 294 WP_275601170.1 competence type IV pilus minor pilin ComGE Machinery gene
  M8286_RS00755 (M8286_00750) comGF/cglF 121949..122383 (+) 435 WP_275601171.1 competence type IV pilus minor pilin ComGF Machinery gene
  M8286_RS00760 (M8286_00755) comGG 122361..122879 (+) 519 WP_275601172.1 competence type IV pilus minor pilin ComGG -
  M8286_RS00765 (M8286_00760) comYH 122929..123882 (+) 954 WP_275601173.1 class I SAM-dependent methyltransferase Machinery gene
  M8286_RS00770 (M8286_00765) - 123932..125119 (+) 1188 WP_167787180.1 acetate kinase -
  M8286_RS00775 (M8286_00770) - 125434..125985 (+) 552 WP_275601174.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38991.01 Da        Isoelectric Point: 9.1394

>NTDB_id=690313 M8286_RS00735 WP_358639410.1 119989..121026(+) (comYB) [Streptococcus suis strain 3112]
MRKLIAFLQQDISVFGRQKQKKLPLVRQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
SDLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLGLVGVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=690313 M8286_RS00735 WP_358639410.1 119989..121026(+) (comYB) [Streptococcus suis strain 3112]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGTTCG
CCAGCGTAAGGTCATTGAGCTCTTCAACAATCTCTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCTTATACCCAGGTCTTGTCAGACGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTT
TCGGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTTAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TAGGTTTTCTGCTCTTGATTATGCTGGGCTTGAAAAACTATCTGTTGCCCCAGTTGGAGGAAGGCAATGCAGCTACTATG
CTAATTAACCATCTACCGACTATCTTTTTATCCCTCTGTGGACTTGGTTTGGTGGGGGTCTTGGCCGGTATGGTTTGGTT
TCGCAAAACCAACAAAATCAAGGTCTTTTCCTGCTTAGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAGGAG
CAGCAGTCGCAGCTCTTTCGAGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
CAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCAGAGTGCTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comGB/cglB Streptococcus mitis NCTC 12261

60.896

97.101

0.591
  comYB Streptococcus mutans UA140

59.475

99.42

0.591
  comYB Streptococcus mutans UA159

59.475

99.42

0.591
  comGB/cglB Streptococcus mitis SK321

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae Rx1

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae D39

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae R6

60

97.101

0.583
  comGB/cglB Streptococcus pneumoniae TIGR4

60

97.101

0.583
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493