Detailed information NTG0690316

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: M8286_RS00755
• Genome accession: NZ_CP097577
• Coordinates: 121949..122383 (+)
• Length: 144 a.a.
• NCBI ID: WP_275601171.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 3112
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 116949..127383

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8286_RS00720 (M8286_00715)	-	117689..118063 (+)	375	WP_024385120.1	DUF1033 family protein	-
M8286_RS00725 (M8286_00720)	-	118091..119041 (-)	951	WP_275601166.1	S66 peptidase family protein	-
M8286_RS00730 (M8286_00725)	comYA	119127..120077 (+)	951	WP_275601167.1	competence type IV pilus ATPase ComGA	Machinery gene
M8286_RS00735 (M8286_00730)	comYB	119989..121026 (+)	1038	WP_358639410.1	competence type IV pilus assembly protein ComGB	Machinery gene
M8286_RS00740 (M8286_00735)	comYC	121028..121309 (+)	282	WP_275601168.1	competence type IV pilus major pilin ComGC	Machinery gene
M8286_RS00745 (M8286_00740)	comGD	121290..121697 (+)	408	WP_275601169.1	competence type IV pilus minor pilin ComGD	-
M8286_RS00750 (M8286_00745)	comYE	121669..121962 (+)	294	WP_275601170.1	competence type IV pilus minor pilin ComGE	Machinery gene
M8286_RS00755 (M8286_00750)	comGF/cglF	121949..122383 (+)	435	WP_275601171.1	competence type IV pilus minor pilin ComGF	Machinery gene
M8286_RS00760 (M8286_00755)	comGG	122361..122879 (+)	519	WP_275601172.1	competence type IV pilus minor pilin ComGG	-
M8286_RS00765 (M8286_00760)	comYH	122929..123882 (+)	954	WP_275601173.1	class I SAM-dependent methyltransferase	Machinery gene
M8286_RS00770 (M8286_00765)	-	123932..125119 (+)	1188	WP_167787180.1	acetate kinase	-
M8286_RS00775 (M8286_00770)	-	125434..125985 (+)	552	WP_275601174.1	folate family ECF transporter S component	-
M8286_RS00780 (M8286_00775)	-	126041..127303 (+)	1263	WP_358637879.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16458.78 Da
• Isoelectric Point: 7.2766

>NTDB_id=690316 M8286_RS00755 WP_275601171.1 121949..122383(+) (comGF/cglF) [Streptococcus suis strain 3112]
MLKSKIPAFTLLECLVALVILSGSLLVFEGLSKLLVQEVHHQNQTIQKEWLVFSSQLRSEWDQADLVKVENGRVYVDKGG
QALAFGKSRSDDFRKTNDRGQGYQPMLYHLDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=690316 M8286_RS00755 WP_275601171.1 121949..122383(+) (comGF/cglF) [Streptococcus suis strain 3112]
TTGTTAAAAAGTAAAATTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCCTTAGTCATTCTTTCAGGTAGTCTTCTGGT
CTTTGAAGGCTTGTCCAAATTGCTGGTTCAAGAGGTACATCATCAAAATCAAACCATTCAAAAGGAATGGTTGGTCTTCT
CTAGTCAATTGCGGTCGGAGTGGGACCAGGCGGACTTGGTCAAGGTTGAAAATGGCAGGGTCTATGTTGATAAGGGAGGT
CAGGCTTTGGCCTTTGGTAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGGGGACAGGGCTACCAGCCCATGCT
CTATCATCTAGACAGCGCAGCTATTTCCCAAGAAAACCAGCTGGTGCGTATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	55.319	97.917	0.542
comGF/cglF	Streptococcus pneumoniae Rx1	55.319	97.917	0.542
comGF/cglF	Streptococcus pneumoniae D39	55.319	97.917	0.542
comGF/cglF	Streptococcus pneumoniae R6	55.319	97.917	0.542
comGF/cglF	Streptococcus mitis NCTC 12261	55.97	93.056	0.521
comGF/cglF	Streptococcus mitis SK321	52.985	93.056	0.493
comYF	Streptococcus mutans UA140	48.611	100	0.486
comYF	Streptococcus mutans UA159	47.917	100	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	47.518	97.917	0.465