Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SMUNUM_RS09340 Genome accession   NZ_AP014571
Coordinates   1885343..1886284 (-) Length   313 a.a.
NCBI ID   WP_002263435.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1880343..1891284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS09300 (SMNUM_1767) - 1880352..1881551 (-) 1200 WP_002263443.1 acetate kinase -
  SMUNUM_RS09305 (SMNUM_1768) comYH 1881610..1882563 (-) 954 WP_019805509.1 class I SAM-dependent methyltransferase Machinery gene
  SMUNUM_RS09310 (SMNUM_1769) comYG 1882618..1883007 (-) 390 WP_019805510.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMUNUM_RS09315 (SMNUM_1770) comYF 1882985..1883419 (-) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMUNUM_RS09320 (SMNUM_1771) comYE 1883406..1883699 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMUNUM_RS09325 (SMNUM_1772) comYD 1883671..1884075 (-) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMUNUM_RS09330 (SMNUM_1773) comYC 1884062..1884376 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMUNUM_RS09335 (SMNUM_1774) comYB 1884376..1885407 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMUNUM_RS09340 (SMNUM_1775) comYA 1885343..1886284 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  SMUNUM_RS09345 (SMNUM_1776) - 1886414..1886797 (-) 384 WP_019805511.1 DUF1033 family protein -
  SMUNUM_RS09350 (SMNUM_1777) rpoC 1886925..1890554 (-) 3630 WP_002263433.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35739.09 Da        Isoelectric Point: 8.0347

>NTDB_id=66011 SMUNUM_RS09340 WP_002263435.1 1885343..1886284(-) (comYA) [Streptococcus mutans LP13]
MVQKLGRKIIAEAVQNKAQDIYIIPKKESYELYMRIGNERRFIDVYDHHFMANLISHFKFVAGMNVGEKRRSQLGSCDYS
YDEGKVISLRLSSVGDYRGYESLVIRLLFSGRHDLKFWFNSMDLILNEIKGRGLYLFSGPVGSGKTSLMYQLVKLRFETK
QVITIEDPVEIKQDNMLQLQLNESIDMTYDNLIKLSLRHRPDILIIGEIRDKETARAVIRASLTGAMVFSTIHAKSIPGV
YARMLELGTSSEELQNALRGIVYQRLIGGGGIIDFAKGDYQNHSAKKWNKQIYDLFTAGYITEGEAQAEEIED

Nucleotide


Download         Length: 942 bp        

>NTDB_id=66011 SMUNUM_RS09340 WP_002263435.1 1885343..1886284(-) (comYA) [Streptococcus mutans LP13]
ATGGTTCAAAAATTAGGTAGAAAAATCATTGCCGAAGCTGTTCAAAATAAAGCACAAGATATCTATATTATTCCTAAAAA
AGAATCTTATGAGCTTTATATGAGAATAGGGAATGAAAGGAGGTTCATTGATGTTTATGACCATCATTTCATGGCTAATC
TTATTAGTCACTTTAAATTTGTTGCAGGAATGAATGTTGGTGAGAAAAGACGAAGTCAGCTGGGCTCTTGTGATTATTCT
TATGATGAAGGGAAAGTTATTTCATTAAGGTTATCAAGTGTAGGAGATTATCGTGGTTATGAAAGTTTGGTTATTCGCTT
ACTTTTTTCTGGACGTCACGATTTAAAATTCTGGTTTAACAGTATGGATTTGATTTTAAATGAAATCAAGGGGCGAGGGC
TTTATCTTTTTTCAGGTCCAGTTGGAAGTGGCAAAACAAGTTTGATGTATCAATTGGTAAAACTAAGATTTGAGACCAAA
CAGGTAATTACCATTGAAGATCCTGTGGAAATTAAGCAAGATAATATGTTACAACTGCAGCTTAATGAAAGCATTGATAT
GACTTATGATAATTTAATTAAATTATCTCTGAGGCATCGTCCGGATATTTTAATTATTGGAGAAATTCGAGATAAAGAAA
CCGCCAGAGCTGTTATTAGAGCAAGTCTTACAGGGGCAATGGTATTCTCAACTATCCATGCTAAAAGCATTCCAGGTGTT
TATGCTAGGATGTTAGAATTGGGTACTAGTTCAGAAGAATTACAAAATGCTTTGCGTGGTATTGTTTATCAACGTTTAAT
AGGGGGAGGAGGGATTATTGACTTTGCCAAAGGGGATTATCAAAACCACTCAGCAAAAAAGTGGAACAAACAAATTTATG
ACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

100

100

1
  comYA Streptococcus mutans UA140

99.681

100

0.997
  comYA Streptococcus gordonii str. Challis substr. CH1

67.093

100

0.671
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.026

99.681

0.658
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

99.361

0.655
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

99.361

0.521

Multiple sequence alignment