Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   SMUNUM_RS09320 Genome accession   NZ_AP014571
Coordinates   1883406..1883699 (-) Length   97 a.a.
NCBI ID   WP_002263439.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1878406..1888699
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS09290 (SMNUM_1765) - 1878806..1879051 (-) 246 WP_002268893.1 helix-turn-helix transcriptional regulator -
  SMUNUM_RS09295 tnpA 1879676..1880139 (-) 464 Protein_1786 IS200/IS605 family transposase -
  SMUNUM_RS09300 (SMNUM_1767) - 1880352..1881551 (-) 1200 WP_002263443.1 acetate kinase -
  SMUNUM_RS09305 (SMNUM_1768) comYH 1881610..1882563 (-) 954 WP_019805509.1 class I SAM-dependent methyltransferase Machinery gene
  SMUNUM_RS09310 (SMNUM_1769) comYG 1882618..1883007 (-) 390 WP_019805510.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMUNUM_RS09315 (SMNUM_1770) comYF 1882985..1883419 (-) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMUNUM_RS09320 (SMNUM_1771) comYE 1883406..1883699 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMUNUM_RS09325 (SMNUM_1772) comYD 1883671..1884075 (-) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMUNUM_RS09330 (SMNUM_1773) comYC 1884062..1884376 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMUNUM_RS09335 (SMNUM_1774) comYB 1884376..1885407 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMUNUM_RS09340 (SMNUM_1775) comYA 1885343..1886284 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  SMUNUM_RS09345 (SMNUM_1776) - 1886414..1886797 (-) 384 WP_019805511.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11001.91 Da        Isoelectric Point: 9.4908

>NTDB_id=66007 SMUNUM_RS09320 WP_002263439.1 1883406..1883699(-) (comYE) [Streptococcus mutans LP13]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALQTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=66007 SMUNUM_RS09320 WP_002263439.1 1883406..1883699(-) (comYE) [Streptococcus mutans LP13]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGACTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

100

100

1
  comYE Streptococcus mutans UA159

100

100

1
  comGE/cglE Streptococcus pneumoniae Rx1

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae D39

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae R6

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae TIGR4

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis NCTC 12261

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis SK321

44.444

92.784

0.412

Multiple sequence alignment