Detailed information NTG0066006

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: SMUNUM_RS09315
• Genome accession: NZ_AP014571
• Coordinates: 1882985..1883419 (-)
• Length: 144 a.a.
• NCBI ID: WP_002263440.1
• Uniprot ID: -
• Organism: Streptococcus mutans LP13
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1877985..1888419

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNUM_RS09285 (SMNUM_1764)	-	1878397..1878837 (-)	441	WP_002264006.1	hypothetical protein	-
SMUNUM_RS09290 (SMNUM_1765)	-	1878806..1879051 (-)	246	WP_002268893.1	helix-turn-helix transcriptional regulator	-
SMUNUM_RS09295	tnpA	1879676..1880139 (-)	464	Protein_1786	IS200/IS605 family transposase	-
SMUNUM_RS09300 (SMNUM_1767)	-	1880352..1881551 (-)	1200	WP_002263443.1	acetate kinase	-
SMUNUM_RS09305 (SMNUM_1768)	comYH	1881610..1882563 (-)	954	WP_019805509.1	class I SAM-dependent methyltransferase	Machinery gene
SMUNUM_RS09310 (SMNUM_1769)	comYG	1882618..1883007 (-)	390	WP_019805510.1	competence type IV pilus minor pilin ComGG	Machinery gene
SMUNUM_RS09315 (SMNUM_1770)	comYF	1882985..1883419 (-)	435	WP_002263440.1	competence type IV pilus minor pilin ComGF	Machinery gene
SMUNUM_RS09320 (SMNUM_1771)	comYE	1883406..1883699 (-)	294	WP_002263439.1	competence type IV pilus minor pilin ComGE	Machinery gene
SMUNUM_RS09325 (SMNUM_1772)	comYD	1883671..1884075 (-)	405	WP_002264246.1	competence type IV pilus minor pilin ComGD	Machinery gene
SMUNUM_RS09330 (SMNUM_1773)	comYC	1884062..1884376 (-)	315	WP_002263437.1	competence type IV pilus major pilin ComGC	Machinery gene
SMUNUM_RS09335 (SMNUM_1774)	comYB	1884376..1885407 (-)	1032	WP_255262721.1	competence type IV pilus assembly protein ComGB	Machinery gene
SMUNUM_RS09340 (SMNUM_1775)	comYA	1885343..1886284 (-)	942	WP_002263435.1	competence type IV pilus ATPase ComGA	Machinery gene
SMUNUM_RS09345 (SMNUM_1776)	-	1886414..1886797 (-)	384	WP_019805511.1	DUF1033 family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16266.75 Da
• Isoelectric Point: 9.9512

>NTDB_id=66006 SMUNUM_RS09315 WP_002263440.1 1882985..1883419(-) (comYF) [Streptococcus mutans LP13]
MLKSKLKAFTLLECLLALLVIAGSVSVYNGLTKAISSNIHYLSKNQEDAWLLFCQQFRSELEGTTLQKLDSNKLYIQKNN
QSLAFGKSKASDFRKTNSDGRGYQPMLTEIKAANFSQSGKIIKLDLTFKDGLERTFVYAFHEKN

Nucleotide

• Length: 435 bp

>NTDB_id=66006 SMUNUM_RS09315 WP_002263440.1 1882985..1883419(-) (comYF) [Streptococcus mutans LP13]
TTGTTAAAAAGTAAATTGAAAGCTTTCACACTTTTAGAGTGTCTCCTTGCTTTGCTTGTCATTGCTGGTAGTGTATCTGT
TTATAATGGTCTAACTAAAGCTATTAGTAGTAATATTCATTACTTATCAAAAAATCAAGAAGATGCTTGGTTACTTTTTT
GTCAGCAATTTCGGTCTGAACTTGAAGGAACGACTTTGCAAAAATTGGATAGCAATAAGCTTTATATTCAAAAAAATAAT
CAAAGTTTAGCCTTTGGTAAATCAAAAGCAAGTGATTTTAGAAAGACTAACAGTGATGGACGTGGTTATCAGCCTATGTT
GACGGAGATCAAAGCTGCTAATTTTAGTCAATCAGGAAAAATTATTAAATTAGACCTTACTTTCAAAGATGGTTTAGAAA
GGACTTTTGTTTATGCTTTTCATGAAAAAAATTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (36-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA159	100	100	1
comYF	Streptococcus mutans UA140	99.306	100	0.993
comGF	Lactococcus lactis subsp. cremoris KW2	43.262	97.917	0.424
comGF/cglF	Streptococcus pneumoniae Rx1	40.299	93.056	0.375
comGF/cglF	Streptococcus pneumoniae D39	40.299	93.056	0.375
comGF/cglF	Streptococcus pneumoniae R6	40.299	93.056	0.375
comGF/cglF	Streptococcus pneumoniae TIGR4	40.299	93.056	0.375
comGF/cglF	Streptococcus mitis NCTC 12261	38.806	93.056	0.361