Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ANG_RS10070 Genome accession   NZ_AP013072
Coordinates   2021092..2022033 (-) Length   313 a.a.
NCBI ID   WP_006268058.1    Uniprot ID   F9P809
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2016092..2027033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS10030 (ANG_2035) - 2016149..2017348 (-) 1200 WP_003035323.1 acetate kinase -
  ANG_RS10035 (ANG_2036) - 2017395..2018348 (-) 954 Protein_1984 class I SAM-dependent methyltransferase -
  ANG_RS10040 (ANG_2037) comGG 2018433..2018759 (-) 327 WP_020999447.1 competence type IV pilus minor pilin ComGG -
  ANG_RS10045 (ANG_2038) comGF/cglF 2018740..2019177 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  ANG_RS10050 (ANG_2039) comGE/cglE 2019161..2019454 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  ANG_RS10055 (ANG_2040) comYD 2019426..2019854 (-) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  ANG_RS10060 (ANG_2041) comYC 2019814..2020131 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  ANG_RS10065 (ANG_2042) comYB 2020128..2021150 (-) 1023 WP_038677372.1 competence type IV pilus assembly protein ComGB Machinery gene
  ANG_RS10070 (ANG_2043) comYA 2021092..2022033 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  ANG_RS10075 (ANG_2044) - 2022103..2022468 (-) 366 WP_022525692.1 DUF1033 family protein -
  ANG_RS10080 (ANG_2045) glnA 2022656..2024002 (-) 1347 WP_025272015.1 type I glutamate--ammonia ligase -
  ANG_RS10085 (ANG_2046) - 2024041..2024400 (-) 360 WP_003073972.1 MerR family transcriptional regulator -
  ANG_RS10090 (ANG_2047) - 2024477..2025007 (-) 531 WP_003033434.1 FUSC family protein -
  ANG_RS10095 (ANG_2048) - 2025522..2026721 (-) 1200 WP_003033487.1 phosphoglycerate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35973.15 Da        Isoelectric Point: 6.3145

>NTDB_id=65556 ANG_RS10070 WP_006268058.1 2021092..2022033(-) (comYA) [Streptococcus anginosus subsp. whileyi MAS624]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YSDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFANQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHEPSDWNKQIDQLYAAGHITFEQAETEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=65556 ANG_RS10070 WP_006268058.1 2021092..2022033(-) (comYA) [Streptococcus anginosus subsp. whileyi MAS624]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTTAAGTTTACTGCTGGGATGAATGTGGGAGAAAAACGTCGCAGTCAGCTGGGCTCTTGCGATTATCAA
TATAGTGACAAGAAAACGTCGCTACGGTTATCAACAGTGGGGGATTATCGCGGATATGAAAGTCTAGTGATTCGTCTATT
GCATGATGAAGAAGCAGAGCTGAAGTTTTGGTTTGCTCAAATTCCGGAGTTGAAAGAACGTTTCAAACAGCGAGGGCTTT
ACCTTTTTTCAGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCAATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAGCATGAGCCAAGTGACTGGAATAAGCAGATTGATCAGC
TTTATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P809

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

83.226

99.042

0.824
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

76.038

100

0.76
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.719

100

0.757
  comYA Streptococcus mutans UA159

64.63

99.361

0.642
  comYA Streptococcus mutans UA140

64.63

99.361

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.662

99.361

0.543
  comGA Latilactobacillus sakei subsp. sakei 23K

43.478

88.179

0.383

Multiple sequence alignment