Detailed information NTG0065554

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: ANG_RS10060
• Genome accession: NZ_AP013072
• Coordinates: 2019814..2020131 (-)
• Length: 105 a.a.
• NCBI ID: WP_020998068.1
• Uniprot ID: U2XY26
• Organism: Streptococcus anginosus subsp. whileyi MAS624
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2014814..2025131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ANG_RS10030 (ANG_2035)	-	2016149..2017348 (-)	1200	WP_003035323.1	acetate kinase	-
ANG_RS10035 (ANG_2036)	-	2017395..2018348 (-)	954	Protein_1984	class I SAM-dependent methyltransferase	-
ANG_RS10040 (ANG_2037)	comGG	2018433..2018759 (-)	327	WP_020999447.1	competence type IV pilus minor pilin ComGG	-
ANG_RS10045 (ANG_2038)	comGF/cglF	2018740..2019177 (-)	438	WP_003035329.1	competence type IV pilus minor pilin ComGF	Machinery gene
ANG_RS10050 (ANG_2039)	comGE/cglE	2019161..2019454 (-)	294	WP_003035318.1	competence type IV pilus minor pilin ComGE	Machinery gene
ANG_RS10055 (ANG_2040)	comYD	2019426..2019854 (-)	429	WP_020999411.1	competence type IV pilus minor pilin ComGD	Machinery gene
ANG_RS10060 (ANG_2041)	comYC	2019814..2020131 (-)	318	WP_020998068.1	competence type IV pilus major pilin ComGC	Machinery gene
ANG_RS10065 (ANG_2042)	comYB	2020128..2021150 (-)	1023	WP_038677372.1	competence type IV pilus assembly protein ComGB	Machinery gene
ANG_RS10070 (ANG_2043)	comYA	2021092..2022033 (-)	942	WP_006268058.1	competence type IV pilus ATPase ComGA	Machinery gene
ANG_RS10075 (ANG_2044)	-	2022103..2022468 (-)	366	WP_022525692.1	DUF1033 family protein	-
ANG_RS10080 (ANG_2045)	glnA	2022656..2024002 (-)	1347	WP_025272015.1	type I glutamate--ammonia ligase	-
ANG_RS10085 (ANG_2046)	-	2024041..2024400 (-)	360	WP_003073972.1	MerR family transcriptional regulator	-
ANG_RS10090 (ANG_2047)	-	2024477..2025007 (-)	531	WP_003033434.1	FUSC family protein	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11678.82 Da
• Isoelectric Point: 10.1006

>NTDB_id=65554 ANG_RS10060 WP_020998068.1 2019814..2020131(-) (comYC) [Streptococcus anginosus subsp. whileyi MAS624]
MKKIKNIKVKAFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVSEGT
ITDKQAVSYKAYYAKHTKEARTVAD

Nucleotide

• Length: 318 bp

>NTDB_id=65554 ANG_RS10060 WP_020998068.1 2019814..2020131(-) (comYC) [Streptococcus anginosus subsp. whileyi MAS624]
ATGAAAAAAATTAAAAATATAAAGGTAAAAGCTTTCACTTTGGTAGAAATGTTAGTGGTGCTTCTAATCATCAGTGTTTT
GATGCTTTTGTTTGTTCCGAATTTGACCAAACAAAAAGAAGCTGTAACGGAAAAAGGAAATGCAGCTGTTGTGAAGGTTG
TCGAAAGTCAGGCAGAGCTTTTTGAAGTGAATCATACTAATGAAAAAGCGACGCTTTCAAAATTAGTCAGTGAAGGAACT
ATTACAGACAAGCAAGCAGTATCATACAAGGCTTATTATGCAAAACATACAAAAGAAGCTCGCACAGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: U2XY26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	72.381	100	0.724
comYC	Streptococcus mutans UA140	68.571	100	0.686
comYC	Streptococcus mutans UA159	68.571	100	0.686
comGC/cglC	Streptococcus mitis NCTC 12261	69.608	97.143	0.676
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC	Lactococcus lactis subsp. cremoris KW2	55.769	99.048	0.552
comYC	Streptococcus suis isolate S10	64.045	84.762	0.543