Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   ANG_RS10045 Genome accession   NZ_AP013072
Coordinates   2018740..2019177 (-) Length   145 a.a.
NCBI ID   WP_003035329.1    Uniprot ID   F9P803
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2013740..2024177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS10025 (ANG_2034) glmS 2013945..2015759 (-) 1815 WP_020999448.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -
  ANG_RS10030 (ANG_2035) - 2016149..2017348 (-) 1200 WP_003035323.1 acetate kinase -
  ANG_RS10035 (ANG_2036) - 2017395..2018348 (-) 954 Protein_1984 class I SAM-dependent methyltransferase -
  ANG_RS10040 (ANG_2037) comGG 2018433..2018759 (-) 327 WP_020999447.1 competence type IV pilus minor pilin ComGG -
  ANG_RS10045 (ANG_2038) comGF/cglF 2018740..2019177 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  ANG_RS10050 (ANG_2039) comGE/cglE 2019161..2019454 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  ANG_RS10055 (ANG_2040) comYD 2019426..2019854 (-) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  ANG_RS10060 (ANG_2041) comYC 2019814..2020131 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  ANG_RS10065 (ANG_2042) comYB 2020128..2021150 (-) 1023 WP_038677372.1 competence type IV pilus assembly protein ComGB Machinery gene
  ANG_RS10070 (ANG_2043) comYA 2021092..2022033 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  ANG_RS10075 (ANG_2044) - 2022103..2022468 (-) 366 WP_022525692.1 DUF1033 family protein -
  ANG_RS10080 (ANG_2045) glnA 2022656..2024002 (-) 1347 WP_025272015.1 type I glutamate--ammonia ligase -

Sequence

Protein


Download         Length: 145 a.a.        Molecular weight: 16865.57 Da        Isoelectric Point: 10.6422

>NTDB_id=65551 ANG_RS10045 WP_003035329.1 2018740..2019177(-) (comGF/cglF) [Streptococcus anginosus subsp. whileyi MAS624]
MFKANKVKAFTLLEALVALFVISGSVLLFQSMTRLLASEVRARQHSEQREWLLFAHQLEAELIRSSFEKVENNRLYMKQD
GKTIAFGKSSGQDFRKTNANGKGYQPMIYNVKKAEISQKNELIHIRMTFKRGLEREFVYRVETKS

Nucleotide


Download         Length: 438 bp        

>NTDB_id=65551 ANG_RS10045 WP_003035329.1 2018740..2019177(-) (comGF/cglF) [Streptococcus anginosus subsp. whileyi MAS624]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACACTTTTAGAGGCTCTGGTTGCCCTCTTTGTAATCAGCGGGAGTGTGCT
ATTATTTCAATCGATGACGCGTCTTCTGGCTTCGGAGGTCCGAGCTCGACAACACAGTGAACAACGAGAATGGCTTTTGT
TTGCCCATCAATTAGAAGCGGAATTGATTCGTTCTTCATTTGAAAAAGTGGAGAATAATCGTTTATACATGAAGCAGGAC
GGTAAGACGATTGCATTTGGAAAGTCAAGTGGACAAGATTTCAGAAAAACCAATGCAAATGGGAAAGGCTATCAGCCTAT
GATTTATAATGTGAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATATCAGAATGACATTTAAGCGAGGATTGG
AAAGGGAGTTCGTCTATCGTGTGGAAACAAAGAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(39-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P803

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae R6

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae TIGR4

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae Rx1

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae D39

66.429

96.552

0.641
  comGF/cglF Streptococcus mitis NCTC 12261

65.714

96.552

0.634
  comGF/cglF Streptococcus mitis SK321

65.714

96.552

0.634
  comYF Streptococcus mutans UA159

43.972

97.241

0.428
  comYF Streptococcus mutans UA140

43.972

97.241

0.428
  comGF Lactococcus lactis subsp. cremoris KW2

42.963

93.103

0.4

Multiple sequence alignment