Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   L3475_RS09645 Genome accession   NZ_CP091451
Coordinates   1857775..1858254 (-) Length   159 a.a.
NCBI ID   WP_000588897.1    Uniprot ID   Q9R2W8
Organism   Streptococcus pneumoniae strain 3238/09     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1852775..1863254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3475_RS09645 (L3475_09570) comX/comX2 1857775..1858254 (-) 480 WP_000588897.1 sigma-70 family RNA polymerase sigma factor Regulator
  L3475_RS09650 (L3475_09575) nusG 1858376..1858912 (-) 537 WP_000376736.1 transcription termination/antitermination protein NusG -
  L3475_RS09655 (L3475_09580) secE 1858967..1859143 (-) 177 WP_001210991.1 preprotein translocase subunit SecE -
  L3475_RS09660 (L3475_09585) rpmG 1859153..1859305 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  L3475_RS09665 (L3475_09590) pbp2a 1859358..1861553 (-) 2196 WP_000762617.1 penicillin-binding protein PBP2A -
  L3475_RS09670 (L3475_09595) - 1861640..1862515 (+) 876 WP_001811920.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19873.52 Da        Isoelectric Point: 7.3797

>NTDB_id=651352 L3475_RS09645 WP_000588897.1 1857775..1858254(-) (comX/comX2) [Streptococcus pneumoniae strain 3238/09]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=651352 L3475_RS09645 WP_000588897.1 1857775..1858254(-) (comX/comX2) [Streptococcus pneumoniae strain 3238/09]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTTTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGAGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9R2W8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

100

100

1
  comX/comX1 Streptococcus pneumoniae Rx1

100

100

1
  comX/comX2 Streptococcus pneumoniae D39

100

100

1
  comX/comX1 Streptococcus pneumoniae D39

100

100

1
  comX/comX2 Streptococcus pneumoniae R6

100

100

1
  comX/comX1 Streptococcus pneumoniae R6

100

100

1
  comX/comX2 Streptococcus pneumoniae TIGR4

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae TIGR4

99.371

100

0.994
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

92.453

100

0.925
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

92.453

100

0.925
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

90.566

100

0.906
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

89.241

99.371

0.887
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comX/sigX Streptococcus mutans UA159

46

94.34

0.434
  comX/sigX Streptococcus suis isolate S10

45.695

94.969

0.434
  comX/sigX Streptococcus suis D9

45.695

94.969

0.434
  comX/sigX Streptococcus suis P1/7

45.695

94.969

0.434
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

94.34

0.377