Detailed information NTG0646002

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: L1A18_RS09360
• Genome accession: NZ_CP090887
• Coordinates: 1822801..1823280 (-)
• Length: 159 a.a.
• NCBI ID: WP_000588873.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NP7536
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1821820..1822773	1822801..1823280	flank	28

Gene organization within MGE regions

Location: 1821820..1823280

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A18_RS09355 (L1A18_09355)	-	1821820..1822773 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
L1A18_RS09360 (L1A18_09360)	comX/comX2	1822801..1823280 (-)	480	WP_000588873.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19845.50 Da
• Isoelectric Point: 7.3795

>NTDB_id=646002 L1A18_RS09360 WP_000588873.1 1822801..1823280(-) (comX/comX2) [Streptococcus pneumoniae strain NP7536]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRK
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=646002 L1A18_RS09360 WP_000588873.1 1822801..1823280(-) (comX/comX2) [Streptococcus pneumoniae strain NP7536]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTTTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAAA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/comX1	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	89.937	100	0.899
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	88.608	99.371	0.881
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	49.359	98.113	0.484
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	49.359	98.113	0.484
comX/sigX	Streptococcus suis D9	46.358	94.969	0.44
comX/sigX	Streptococcus suis isolate S10	46.358	94.969	0.44
comX/sigX	Streptococcus suis P1/7	46.358	94.969	0.44
comX/sigX	Streptococcus mutans UA159	45.333	94.34	0.428
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	94.34	0.377