Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   LK450_RS08255 Genome accession   NZ_CP085939
Coordinates   1670193..1671134 (+) Length   313 a.a.
NCBI ID   WP_003032308.1    Uniprot ID   -
Organism   Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1665193..1676134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK450_RS08230 (LK450_08230) - 1665505..1666704 (+) 1200 WP_003032298.1 phosphoglycerate kinase -
  LK450_RS08235 (LK450_08235) - 1667219..1667749 (+) 531 WP_003032280.1 aromatic acid exporter family protein -
  LK450_RS08240 (LK450_08240) - 1667826..1668185 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  LK450_RS08245 (LK450_08245) glnA 1668224..1669570 (+) 1347 WP_003032299.1 type I glutamate--ammonia ligase -
  LK450_RS08250 (LK450_08250) - 1669758..1670123 (+) 366 WP_003032307.1 DUF1033 family protein -
  LK450_RS08255 (LK450_08255) comYA 1670193..1671134 (+) 942 WP_003032308.1 competence type IV pilus ATPase ComGA Machinery gene
  LK450_RS08260 (LK450_08260) comYB 1671076..1672098 (+) 1023 WP_037582505.1 competence type IV pilus assembly protein ComGB Machinery gene
  LK450_RS08265 (LK450_08265) comYC 1672095..1672412 (+) 318 WP_003026997.1 competence type IV pilus major pilin ComGC Machinery gene
  LK450_RS08270 (LK450_08270) comYD 1672372..1672800 (+) 429 WP_050791305.1 competence type IV pilus minor pilin ComGD Machinery gene
  LK450_RS08275 (LK450_08275) comGE/cglE 1672772..1673065 (+) 294 WP_003032294.1 competence type IV pilus minor pilin ComGE Machinery gene
  LK450_RS08280 (LK450_08280) comGF/cglF 1673049..1673486 (+) 438 WP_003032293.1 competence type IV pilus minor pilin ComGF Machinery gene
  LK450_RS08285 (LK450_08285) comGG 1673467..1673793 (+) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  LK450_RS08290 (LK450_08290) comYH 1673878..1674831 (+) 954 WP_003032282.1 class I SAM-dependent methyltransferase Machinery gene
  LK450_RS08295 (LK450_08295) - 1674878..1676077 (+) 1200 WP_003032291.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35936.14 Da        Isoelectric Point: 6.4197

>NTDB_id=621428 LK450_RS08255 WP_003032308.1 1670193..1671134(+) (comYA) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YSDRKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFANQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKVVLQGICYQRLIAKGGIVDFVSEKYQEHEPIDWNRQIDQLHAAGHINLEQAEAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=621428 LK450_RS08255 WP_003032308.1 1670193..1671134(+) (comYA) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTCAAGTTTACTGCTGGGATGAATGTGGGAGAAAAACGTCGCAGTCAGCTGGGCTCTTGTGATTATCAA
TATAGTGACAGGAAAACGTCGCTACGGTTGTCAACAGTAGGGGATTACCGTGGATATGAAAGCCTGGTGATTCGTCTATT
GCATGATGAAGAAGCAGAGCTGAAGTTTTGGTTTGCTCAAATTCCGGAGTTGAAAGAACGTTTCAAACAGCGAGGGCTTT
ACCTTTTTTCAGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCAATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCCGAGCTGAAAGTTGTCTTACAAGGGATTTGTTACCAACGCTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAGAAGTATCAAGAACACGAGCCAATCGATTGGAATAGGCAGATTGATCAGC
TTCATGCAGCAGGACATATCAATCTTGAGCAGGCAGAAGCGGAAAAAATTATCCACAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

82.903

99.042

0.821
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.08

100

0.751
  comYA Streptococcus mutans UA159

64.309

99.361

0.639
  comYA Streptococcus mutans UA140

64.309

99.361

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

44.444

83.387

0.371