Detailed information NTG0621433

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: LK450_RS08280
• Genome accession: NZ_CP085939
• Coordinates: 1673049..1673486 (+)
• Length: 145 a.a.
• NCBI ID: WP_003032293.1
• Uniprot ID: -
• Organism: Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1668049..1678486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LK450_RS08245 (LK450_08245)	glnA	1668224..1669570 (+)	1347	WP_003032299.1	type I glutamate--ammonia ligase	-
LK450_RS08250 (LK450_08250)	-	1669758..1670123 (+)	366	WP_003032307.1	DUF1033 family protein	-
LK450_RS08255 (LK450_08255)	comYA	1670193..1671134 (+)	942	WP_003032308.1	competence type IV pilus ATPase ComGA	Machinery gene
LK450_RS08260 (LK450_08260)	comYB	1671076..1672098 (+)	1023	WP_037582505.1	competence type IV pilus assembly protein ComGB	Machinery gene
LK450_RS08265 (LK450_08265)	comYC	1672095..1672412 (+)	318	WP_003026997.1	competence type IV pilus major pilin ComGC	Machinery gene
LK450_RS08270 (LK450_08270)	comYD	1672372..1672800 (+)	429	WP_050791305.1	competence type IV pilus minor pilin ComGD	Machinery gene
LK450_RS08275 (LK450_08275)	comGE/cglE	1672772..1673065 (+)	294	WP_003032294.1	competence type IV pilus minor pilin ComGE	Machinery gene
LK450_RS08280 (LK450_08280)	comGF/cglF	1673049..1673486 (+)	438	WP_003032293.1	competence type IV pilus minor pilin ComGF	Machinery gene
LK450_RS08285 (LK450_08285)	comGG	1673467..1673793 (+)	327	WP_018543596.1	competence type IV pilus minor pilin ComGG	-
LK450_RS08290 (LK450_08290)	comYH	1673878..1674831 (+)	954	WP_003032282.1	class I SAM-dependent methyltransferase	Machinery gene
LK450_RS08295 (LK450_08295)	-	1674878..1676077 (+)	1200	WP_003032291.1	acetate kinase	-
LK450_RS08300 (LK450_08300)	glmS	1676466..1678280 (+)	1815	WP_022524764.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16706.26 Da
• Isoelectric Point: 9.6893

>NTDB_id=621433 LK450_RS08280 WP_003032293.1 1673049..1673486(+) (comGF/cglF) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MFKANKVKAFTLLEALVALFVISGSVLLFQSMTRLLASEVQARQHSEQREWLLFADQLEAELARSSFEKVENNRLYMKQD
GKVIAFGKSSGQDFRKTNANGKGYQPMVYDVEKAEISQKNELIHIRMTFKRGLEREFVYCVETKS

Nucleotide

• Length: 438 bp

>NTDB_id=621433 LK450_RS08280 WP_003032293.1 1673049..1673486(+) (comGF/cglF) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGTTCAAGGCAAATAAAGTGAAAGCTTTTACCCTTTTAGAGGCTCTGGTTGCCCTCTTTGTCATTAGTGGAAGTGTGTT
GCTGTTTCAATCTATGACGCGCCTTCTAGCTTCTGAAGTCCAAGCTCGTCAACACAGTGAACAACGAGAATGGCTTTTGT
TTGCAGATCAACTAGAAGCAGAGTTGGCTCGTTCTTCATTTGAAAAGGTGGAGAATAATCGTTTATATATGAAACAGGAC
GGCAAGGTGATTGCATTTGGAAAGTCAAGTGGACAGGATTTCAGAAAAACTAATGCGAATGGGAAAGGTTACCAGCCGAT
GGTTTATGATGTGGAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATATCAGAATGACGTTTAAGCGAGGATTGG
AAAGGGAGTTCGTCTATTGTGTGGAAACAAAGAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae R6	65.714	96.552	0.634
comGF/cglF	Streptococcus pneumoniae TIGR4	65.714	96.552	0.634
comGF/cglF	Streptococcus pneumoniae Rx1	65.714	96.552	0.634
comGF/cglF	Streptococcus pneumoniae D39	65.714	96.552	0.634
comGF/cglF	Streptococcus mitis NCTC 12261	65	96.552	0.628
comGF/cglF	Streptococcus mitis SK321	65	96.552	0.628
comYF	Streptococcus mutans UA159	43.571	96.552	0.421
comYF	Streptococcus mutans UA140	43.571	96.552	0.421
comGF	Lactococcus lactis subsp. cremoris KW2	42.537	92.414	0.393