Detailed information NTG0621434

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: LK450_RS08290
• Genome accession: NZ_CP085939
• Coordinates: 1673878..1674831 (+)
• Length: 317 a.a.
• NCBI ID: WP_003032282.1
• Uniprot ID: A0A448AK79
• Organism: Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1668878..1679831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LK450_RS08250 (LK450_08250)	-	1669758..1670123 (+)	366	WP_003032307.1	DUF1033 family protein	-
LK450_RS08255 (LK450_08255)	comYA	1670193..1671134 (+)	942	WP_003032308.1	competence type IV pilus ATPase ComGA	Machinery gene
LK450_RS08260 (LK450_08260)	comYB	1671076..1672098 (+)	1023	WP_037582505.1	competence type IV pilus assembly protein ComGB	Machinery gene
LK450_RS08265 (LK450_08265)	comYC	1672095..1672412 (+)	318	WP_003026997.1	competence type IV pilus major pilin ComGC	Machinery gene
LK450_RS08270 (LK450_08270)	comYD	1672372..1672800 (+)	429	WP_050791305.1	competence type IV pilus minor pilin ComGD	Machinery gene
LK450_RS08275 (LK450_08275)	comGE/cglE	1672772..1673065 (+)	294	WP_003032294.1	competence type IV pilus minor pilin ComGE	Machinery gene
LK450_RS08280 (LK450_08280)	comGF/cglF	1673049..1673486 (+)	438	WP_003032293.1	competence type IV pilus minor pilin ComGF	Machinery gene
LK450_RS08285 (LK450_08285)	comGG	1673467..1673793 (+)	327	WP_018543596.1	competence type IV pilus minor pilin ComGG	-
LK450_RS08290 (LK450_08290)	comYH	1673878..1674831 (+)	954	WP_003032282.1	class I SAM-dependent methyltransferase	Machinery gene
LK450_RS08295 (LK450_08295)	-	1674878..1676077 (+)	1200	WP_003032291.1	acetate kinase	-
LK450_RS08300 (LK450_08300)	glmS	1676466..1678280 (+)	1815	WP_022524764.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 36123.92 Da
• Isoelectric Point: 4.2586

>NTDB_id=621434 LK450_RS08290 WP_003032282.1 1673878..1674831(+) (comYH) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MNFEKIEQTYMLLLENVQEIQNDLLTSFYDALIEQNGSYLDGDIELDSVRQNNEKLKALKLSKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTQKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDNIATRYEVASRQEHTYAHHLLMEQSLKYLKSGGYAIFLAPNDLLTSSQ
SDLLKTWLQKHAQIVAMIALPEALFGNAAYAKTIFVLQKQEEQAVQLFVYALSDLRDQDDLLEFSEKFQNWSRESEI

Nucleotide

• Length: 954 bp

>NTDB_id=621434 LK450_RS08290 WP_003032282.1 1673878..1674831(+) (comYH) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGAATTTTGAAAAAATTGAACAGACCTATATGCTCTTGTTAGAAAATGTCCAAGAAATCCAAAATGATCTTTTAACGAG
CTTTTATGATGCTTTGATAGAGCAAAATGGCAGCTATCTGGACGGGGATATTGAACTAGATAGTGTTCGGCAGAATAATG
AAAAACTGAAAGCGTTGAAATTAAGTAAAGAGGAATGGCGCCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCTGAGACGATTCTCAATAATACACAAAAAA
ATGTGGATTATCTAGGACTGGAATTGGACGATCTGCTAATTGATATATCAGCCAGTATCGCAGATGTGATGGATGCAAAA
GTTAGTTTTGTGCAAGGTGATGCAGTGCGTCCGCAAGTATTGAAAGAAAGCGATGTGATTATCAGTGATTTACCAGTTGG
CTTTTATCCTGATGATAACATTGCGACGCGCTATGAAGTGGCTAGTAGACAGGAGCATACTTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCAGGCGGTTATGCTATTTTCCTTGCACCAAATGATTTATTGACTAGTTCGCAA
AGTGATTTGCTGAAAACTTGGCTGCAAAAGCATGCCCAGATAGTTGCGATGATTGCATTGCCAGAAGCACTTTTTGGAAA
TGCCGCTTATGCCAAGACAATTTTTGTGCTGCAAAAGCAAGAAGAACAAGCTGTTCAACTGTTTGTTTATGCTTTGTCTG
ATTTGCGAGATCAGGACGATTTATTGGAATTTAGCGAAAAGTTTCAAAATTGGAGCAGAGAAAGTGAAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-299)

3D structure

• AlphaFold DB: A0A448AK79

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	61.27	99.369	0.609
comYH	Streptococcus mutans UA159	60.952	99.369	0.606