Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   LK450_RS08260 Genome accession   NZ_CP085939
Coordinates   1671076..1672098 (+) Length   340 a.a.
NCBI ID   WP_037582505.1    Uniprot ID   -
Organism   Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1666076..1677098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK450_RS08235 (LK450_08235) - 1667219..1667749 (+) 531 WP_003032280.1 aromatic acid exporter family protein -
  LK450_RS08240 (LK450_08240) - 1667826..1668185 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  LK450_RS08245 (LK450_08245) glnA 1668224..1669570 (+) 1347 WP_003032299.1 type I glutamate--ammonia ligase -
  LK450_RS08250 (LK450_08250) - 1669758..1670123 (+) 366 WP_003032307.1 DUF1033 family protein -
  LK450_RS08255 (LK450_08255) comYA 1670193..1671134 (+) 942 WP_003032308.1 competence type IV pilus ATPase ComGA Machinery gene
  LK450_RS08260 (LK450_08260) comYB 1671076..1672098 (+) 1023 WP_037582505.1 competence type IV pilus assembly protein ComGB Machinery gene
  LK450_RS08265 (LK450_08265) comYC 1672095..1672412 (+) 318 WP_003026997.1 competence type IV pilus major pilin ComGC Machinery gene
  LK450_RS08270 (LK450_08270) comYD 1672372..1672800 (+) 429 WP_050791305.1 competence type IV pilus minor pilin ComGD Machinery gene
  LK450_RS08275 (LK450_08275) comGE/cglE 1672772..1673065 (+) 294 WP_003032294.1 competence type IV pilus minor pilin ComGE Machinery gene
  LK450_RS08280 (LK450_08280) comGF/cglF 1673049..1673486 (+) 438 WP_003032293.1 competence type IV pilus minor pilin ComGF Machinery gene
  LK450_RS08285 (LK450_08285) comGG 1673467..1673793 (+) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  LK450_RS08290 (LK450_08290) comYH 1673878..1674831 (+) 954 WP_003032282.1 class I SAM-dependent methyltransferase Machinery gene
  LK450_RS08295 (LK450_08295) - 1674878..1676077 (+) 1200 WP_003032291.1 acetate kinase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39157.24 Da        Isoelectric Point: 9.5231

>NTDB_id=621429 LK450_RS08260 WP_037582505.1 1671076..1672098(+) (comYB) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MQQDISILSRQKRKKLSTVRQKKVVELLNNLFSSGFHLAEIIDFLKRSALLEEVYVDRMKEGLSTGKPFSDIMASLGFSD
NVVTQLSLAELHGNLSLSLSKIEEYLENVSKIKKKLVEVATYPFILFVFLIFIMLGLRNYLLPQLDRQNVATQIISNLPQ
LFLGSLGVVFVLFVIGFYWFQKSSKIAAFHLLARLPFCGTFIQIYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKYYPFFKKELGLIIEYGEVKSKLGRELEVYAQKTWETFFKRVHQAMNVIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=621429 LK450_RS08260 WP_037582505.1 1671076..1672098(+) (comYB) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGCAGCAGGACATATCAATCTTGAGCAGGCAGAAGCGGAAAAAATTATCCACAGTTAGGCAGAAAAAGGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGTGGCTTTCATTTGGCAGAAATTATCGACTTTTTGAAGCGAAGTGCCTTGTTAGAAGAAG
TCTATGTGGACAGGATGAAAGAGGGTTTGTCAACAGGAAAGCCTTTTTCGGACATTATGGCTAGTTTAGGTTTTTCAGAT
AATGTGGTAACACAACTTTCGCTGGCAGAATTACACGGAAATCTCTCACTCAGTCTGAGTAAGATTGAGGAATACTTGGA
AAATGTCTCAAAAATTAAGAAAAAGTTGGTTGAAGTGGCGACTTATCCCTTTATTTTGTTTGTTTTTTTGATATTCATTA
TGCTGGGATTACGTAATTATTTACTCCCGCAACTCGATCGTCAAAATGTAGCAACGCAGATTATCAGTAATTTGCCGCAA
CTTTTTCTGGGTTCATTAGGGGTAGTCTTTGTTTTGTTCGTGATAGGTTTTTATTGGTTTCAGAAAAGCTCCAAAATAGC
AGCATTTCATTTGTTAGCTCGACTTCCTTTTTGTGGAACTTTTATTCAAATCTATTTGACAGCTTATTATGCGAGAGAAT
GGGGAAATATGATTGGTCAAGGTTTAGAACTCAGTCAGATTTTTCAGATGATGCAAGGGCAACGCTCTGCTATGTTTCAA
GAAATTGGAAAAGATTTAGAAGTTGCGCTGCAAAATGGTCAGGAATTTTCACAAGTAGTGAAATATTATCCATTTTTTAA
AAAGGAATTAGGCTTGATAATTGAATACGGTGAAGTGAAATCCAAATTGGGACGTGAATTAGAAGTTTATGCCCAAAAAA
CATGGGAGACATTTTTTAAACGTGTTCATCAAGCGATGAATGTTATTCAGCCACTAGTGTTTGTCTTTGTGGCCTTGATG
ATTGTATTGTTATATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

70.882

100

0.709
  comGB/cglB Streptococcus mitis NCTC 12261

67.761

98.529

0.668
  comGB/cglB Streptococcus mitis SK321

67.463

98.529

0.665
  comGB/cglB Streptococcus pneumoniae TIGR4

67.164

98.529

0.662
  comGB/cglB Streptococcus pneumoniae R6

67.164

98.529

0.662
  comGB/cglB Streptococcus pneumoniae Rx1

67.164

98.529

0.662
  comGB/cglB Streptococcus pneumoniae D39

67.164

98.529

0.662
  comYB Streptococcus mutans UA159

60.35

100

0.609
  comYB Streptococcus mutans UA140

60.058

100

0.606
  comGB Lactococcus lactis subsp. cremoris KW2

51.039

99.118

0.506