Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   NW949_RS07370 Genome accession   NZ_CP102960
Coordinates   1553224..1553499 (-) Length   91 a.a.
NCBI ID   WP_258415261.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 07-G-D     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1548224..1558499
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW949_RS07330 (NW949_07330) - 1549103..1549627 (-) 525 WP_001015123.1 shikimate kinase -
  NW949_RS07335 (NW949_07335) - 1549617..1549763 (-) 147 WP_001789879.1 hypothetical protein -
  NW949_RS07340 (NW949_07340) comGF 1549860..1550357 (-) 498 WP_029694050.1 competence type IV pilus minor pilin ComGF Machinery gene
  NW949_RS07345 (NW949_07345) comGE 1550275..1550574 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  NW949_RS07350 (NW949_07350) comGD 1550561..1551007 (-) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  NW949_RS07355 (NW949_07355) - 1550985..1551050 (-) 66 Protein_1441 competence protein ComGC -
  NW949_RS07360 (NW949_07360) istB 1551112..1551879 (-) 768 WP_001095317.1 IS21-like element helper ATPase IstB -
  NW949_RS07365 (NW949_07365) istA 1551891..1553126 (-) 1236 WP_258410791.1 IS21 family transposase -
  NW949_RS07370 (NW949_07370) comGC 1553224..1553499 (-) 276 WP_258415261.1 competence type IV pilus major pilin ComGC Machinery gene
  NW949_RS07375 (NW949_07375) comGB 1553513..1554583 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  NW949_RS07380 (NW949_07380) comGA 1554555..1555529 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  NW949_RS07385 (NW949_07385) - 1555581..1556204 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  NW949_RS07390 (NW949_07390) - 1556201..1556530 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  NW949_RS07395 (NW949_07395) - 1556530..1557516 (-) 987 WP_000161315.1 ROK family glucokinase -
  NW949_RS07400 (NW949_07400) - 1557513..1557716 (-) 204 WP_000087561.1 YqgQ family protein -

Sequence


Protein


Download         Length: 91 a.a.        Molecular weight: 10169.14 Da        Isoelectric Point: 9.6595

>NTDB_id=619720 NW949_RS07370 WP_258415261.1 1553224..1553499(-) (comGC) [Staphylococcus aureus strain 07-G-D]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAHVNGGYKM

Nucleotide


Download         Length: 276 bp        

>NTDB_id=619720 NW949_RS07370 WP_258415261.1 1553224..1553499(-) (comGC) [Staphylococcus aureus strain 07-G-D]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACATGTAAATGGCGGTTATAAAATGTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

98.81

92.308

0.912

  comGC Staphylococcus aureus N315

98.81

92.308

0.912

  comGC/cglC Streptococcus mitis SK321

46.465

100

0.505

  comGC/cglC Streptococcus pneumoniae R6

45.455

100

0.495

  comGC/cglC Streptococcus pneumoniae D39

45.455

100

0.495

  comGC/cglC Streptococcus pneumoniae TIGR4

45.455

100

0.495

  comGC/cglC Streptococcus pneumoniae Rx1

45.455

100

0.495

  comGC/cglC Streptococcus mitis NCTC 12261

48.913

100

0.495

  comGC Streptococcus suis isolate S10

47.5

87.912

0.418

  comGC Streptococcus gordonii str. Challis substr. CH1

44.048

92.308

0.407

  comGC Lactococcus lactis subsp. cremoris KW2

46.25

87.912

0.407

  comGC Streptococcus mutans UA140

46.835

86.813

0.407

  comGC Streptococcus mutans UA159

46.835

86.813

0.407

  comGC Bacillus subtilis subsp. subtilis str. 168

42.857

84.615

0.363