Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   NW949_RS07380 Genome accession   NZ_CP102960
Coordinates   1554555..1555529 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 07-G-D     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1549555..1560529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW949_RS07335 (NW949_07335) - 1549617..1549763 (-) 147 WP_001789879.1 hypothetical protein -
  NW949_RS07340 (NW949_07340) comGF 1549860..1550357 (-) 498 WP_029694050.1 competence type IV pilus minor pilin ComGF Machinery gene
  NW949_RS07345 (NW949_07345) comGE 1550275..1550574 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  NW949_RS07350 (NW949_07350) comGD 1550561..1551007 (-) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  NW949_RS07355 (NW949_07355) - 1550985..1551050 (-) 66 Protein_1441 competence protein ComGC -
  NW949_RS07360 (NW949_07360) istB 1551112..1551879 (-) 768 WP_001095317.1 IS21-like element helper ATPase IstB -
  NW949_RS07365 (NW949_07365) istA 1551891..1553126 (-) 1236 WP_258410791.1 IS21 family transposase -
  NW949_RS07370 (NW949_07370) comGC 1553224..1553499 (-) 276 WP_258415261.1 competence type IV pilus major pilin ComGC Machinery gene
  NW949_RS07375 (NW949_07375) comGB 1553513..1554583 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  NW949_RS07380 (NW949_07380) comGA 1554555..1555529 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  NW949_RS07385 (NW949_07385) - 1555581..1556204 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  NW949_RS07390 (NW949_07390) - 1556201..1556530 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  NW949_RS07395 (NW949_07395) - 1556530..1557516 (-) 987 WP_000161315.1 ROK family glucokinase -
  NW949_RS07400 (NW949_07400) - 1557513..1557716 (-) 204 WP_000087561.1 YqgQ family protein -
  NW949_RS07405 (NW949_07405) - 1557697..1559160 (-) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  NW949_RS07410 (NW949_07410) - 1559172..1559711 (-) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  NW949_RS07415 (NW949_07415) rpmG 1559920..1560069 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=619722 NW949_RS07380 WP_000697220.1 1554555..1555529(-) (comGA) [Staphylococcus aureus strain 07-G-D]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=619722 NW949_RS07380 WP_000697220.1 1554555..1555529(-) (comGA) [Staphylococcus aureus strain 07-G-D]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAAATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1