Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SII_RS08430 Genome accession   NC_022237
Coordinates   1745453..1746394 (-) Length   313 a.a.
NCBI ID   WP_020999199.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1740453..1751394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS08395 (SII_1653) - 1740504..1741703 (-) 1200 WP_003073996.1 acetate kinase -
  SII_RS08400 (SII_1654) comYH 1741750..1742703 (-) 954 WP_003073994.1 class I SAM-dependent methyltransferase Machinery gene
  SII_RS08405 (SII_1655) comGG 1742794..1743120 (-) 327 WP_020999196.1 competence type IV pilus minor pilin ComGG -
  SII_RS08410 (SII_1656) comGF/cglF 1743101..1743538 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  SII_RS08415 comGE/cglE 1743522..1743815 (-) 294 WP_041823288.1 competence type IV pilus minor pilin ComGE Machinery gene
  SII_RS10330 (SII_1657) comGD 1743796..1744215 (-) 420 Protein_1655 competence type IV pilus minor pilin ComGD -
  SII_RS08420 (SII_1658) comYC 1744175..1744492 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  SII_RS08425 (SII_1659) comYB 1744489..1745511 (-) 1023 WP_020999198.1 competence type IV pilus assembly protein ComGB Machinery gene
  SII_RS08430 (SII_1660) comYA 1745453..1746394 (-) 942 WP_020999199.1 competence type IV pilus ATPase ComGA Machinery gene
  SII_RS08435 (SII_1661) - 1746463..1746828 (-) 366 WP_003075933.1 DUF1033 family protein -
  SII_RS08440 (SII_1662) glnA 1747050..1748396 (-) 1347 WP_020999200.1 type I glutamate--ammonia ligase -
  SII_RS08445 (SII_1663) - 1748435..1748794 (-) 360 WP_003073972.1 MerR family transcriptional regulator -
  SII_RS08450 (SII_1664) - 1748871..1749401 (-) 531 WP_003073971.1 FUSC family protein -
  SII_RS08455 (SII_1665) - 1749576..1750256 (-) 681 WP_003075761.1 COG3942 and LysM peptidoglycan-binding domain-containing protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 36020.40 Da        Isoelectric Point: 7.8524

>NTDB_id=61560 SII_RS08430 WP_020999199.1 1745453..1746394(-) (comYA) [Streptococcus intermedius C270]
MVQNIAQDIICQAKEKQAQDIYFIPKENSYELYMRIGDERRFIQQYAFEKMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YRDKKTSLRLSTVGDYRGYESLVIRLLHDEKAELKFWFAQIPELKGRLKQRGLYLFSGPVGSGKTTLMHQLAQERFADEQ
IMSIEDPVEIKQDRMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDTETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSEKYQEHDPSEWNRQIDQLYAAGHINLEQAKAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=61560 SII_RS08430 WP_020999199.1 1745453..1746394(-) (comYA) [Streptococcus intermedius C270]
ATGGTTCAAAACATTGCACAAGATATTATTTGCCAAGCTAAGGAAAAACAGGCTCAAGATATTTATTTTATCCCAAAGGA
AAATAGTTATGAACTGTACATGAGAATTGGTGATGAGCGACGTTTTATACAACAGTATGCATTTGAAAAGATGGCAGCGG
TGATTAGTCATTTCAAATTTACCGCTGGGATGAATGTTGGTGAAAAACGTAGAAGCCAACTAGGGTCTTGTGATTATCAA
TACAGGGATAAGAAAACGTCACTGCGGTTGTCAACAGTAGGGGATTATCGCGGATATGAAAGTCTTGTGATTCGTTTATT
GCATGATGAAAAAGCAGAGTTGAAGTTTTGGTTTGCTCAAATTCCAGAGTTGAAAGGACGACTCAAGCAACGTGGACTTT
ATCTTTTTTCAGGACCGGTAGGGAGTGGCAAAACCACTCTTATGCATCAGCTGGCTCAAGAACGTTTTGCCGATGAGCAA
ATCATGTCTATCGAAGATCCTGTTGAAATTAAGCAAGACAGAATGTTGCAATTGCAATTGAATGAAGCGATTGGCTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGACATCGTCCAGATTTATTGATTATTGGAGAAATTCGAGATACAGAAACAG
CACGGGCGGTTGTACGAGCCAGCTTGACAGGAGTGACGGTCTTTTCAACGATTCATGCTAAAAGTGTGCGAGGCGTTTAT
GAACGATTGCTAGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTCTTGCAAGGTATTTGTTACCAACGGCTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAAGTATCAAGAACACGATCCAAGCGAATGGAATAGGCAAATTGATCAAC
TTTATGCAGCAGGACATATCAATCTTGAACAGGCAAAAGCGGAAAAAATTATCCACAGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.645

99.042

0.799
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae D39

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae R6

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

74.76

100

0.748
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.226

99.042

0.626
  comGA Lactococcus lactis subsp. cremoris KW2

54.662

99.361

0.543
  comGA Latilactobacillus sakei subsp. sakei 23K

44.015

82.748

0.364

Multiple sequence alignment