Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SII_RS08415 Genome accession   NC_022237
Coordinates   1743522..1743815 (-) Length   97 a.a.
NCBI ID   WP_041823288.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1738522..1748815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS08395 (SII_1653) - 1740504..1741703 (-) 1200 WP_003073996.1 acetate kinase -
  SII_RS08400 (SII_1654) comYH 1741750..1742703 (-) 954 WP_003073994.1 class I SAM-dependent methyltransferase Machinery gene
  SII_RS08405 (SII_1655) comGG 1742794..1743120 (-) 327 WP_020999196.1 competence type IV pilus minor pilin ComGG -
  SII_RS08410 (SII_1656) comGF/cglF 1743101..1743538 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  SII_RS08415 comGE/cglE 1743522..1743815 (-) 294 WP_041823288.1 competence type IV pilus minor pilin ComGE Machinery gene
  SII_RS10330 (SII_1657) comGD 1743796..1744215 (-) 420 Protein_1655 competence type IV pilus minor pilin ComGD -
  SII_RS08420 (SII_1658) comYC 1744175..1744492 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  SII_RS08425 (SII_1659) comYB 1744489..1745511 (-) 1023 WP_020999198.1 competence type IV pilus assembly protein ComGB Machinery gene
  SII_RS08430 (SII_1660) comYA 1745453..1746394 (-) 942 WP_020999199.1 competence type IV pilus ATPase ComGA Machinery gene
  SII_RS08435 (SII_1661) - 1746463..1746828 (-) 366 WP_003075933.1 DUF1033 family protein -
  SII_RS08440 (SII_1662) glnA 1747050..1748396 (-) 1347 WP_020999200.1 type I glutamate--ammonia ligase -
  SII_RS08445 (SII_1663) - 1748435..1748794 (-) 360 WP_003073972.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11038.06 Da        Isoelectric Point: 10.4689

>NTDB_id=61557 SII_RS08415 WP_041823288.1 1743522..1743815(-) (comGE/cglE) [Streptococcus intermedius C270]
MENLRKQYVGGTILLEALLALAIFATIVTLLLGQIHQSRKLENELLKKEEVLRVAKMALQTNQRHLTMNGIEVRVEKSQQ
GIRVYHGKELIFGVQSK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=61557 SII_RS08415 WP_041823288.1 1743522..1743815(-) (comGE/cglE) [Streptococcus intermedius C270]
ATGGAAAATTTAAGAAAACAATATGTTGGAGGGACAATTTTATTAGAAGCACTGCTTGCGTTAGCTATTTTTGCGACAAT
TGTAACTCTGTTGTTGGGACAAATTCACCAGTCTCGAAAACTAGAAAATGAGTTATTAAAAAAAGAAGAAGTCTTAAGGG
TAGCGAAGATGGCCTTGCAAACAAATCAAAGGCATTTAACAATGAACGGTATTGAAGTACGTGTCGAAAAAAGCCAACAA
GGTATTCGGGTTTATCATGGGAAGGAGCTGATTTTTGGTGTTCAAAGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-91)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae D39

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae R6

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae TIGR4

56.522

94.845

0.536
  comGE/cglE Streptococcus mitis NCTC 12261

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis SK321

55.435

94.845

0.526
  comYE Streptococcus mutans UA140

48.352

93.814

0.454
  comYE Streptococcus mutans UA159

48.352

93.814

0.454

Multiple sequence alignment