Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   K6974_RS00800 Genome accession   NZ_CP082204
Coordinates   130481..131431 (+) Length   316 a.a.
NCBI ID   WP_222337410.1    Uniprot ID   -
Organism   Streptococcus suis strain FJSM5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 125481..136431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6974_RS00780 - 127719..127907 (+) 189 Protein_119 helix-turn-helix domain-containing protein -
  K6974_RS00785 (K6974_00770) - 127908..128754 (+) 847 Protein_120 IS630 family transposase -
  K6974_RS00790 (K6974_00775) - 128941..129300 (+) 360 WP_099875663.1 DUF1033 family protein -
  K6974_RS00795 (K6974_00780) - 129445..130395 (-) 951 WP_222337411.1 S66 peptidase family protein -
  K6974_RS00800 (K6974_00785) comYA 130481..131431 (+) 951 WP_222337410.1 competence type IV pilus ATPase ComGA Machinery gene
  K6974_RS00805 (K6974_00790) comYB 131343..132380 (+) 1038 WP_261311719.1 competence type IV pilus assembly protein ComGB Machinery gene
  K6974_RS00810 (K6974_00795) comYC 132382..132663 (+) 282 WP_222337409.1 competence type IV pilus major pilin ComGC Machinery gene
  K6974_RS00815 (K6974_00800) comGD 132644..133051 (+) 408 WP_222337408.1 competence type IV pilus minor pilin ComGD -
  K6974_RS00820 (K6974_00805) comYE 133023..133316 (+) 294 WP_222337407.1 competence type IV pilus minor pilin ComGE Machinery gene
  K6974_RS00825 (K6974_00810) comGF/cglF 133303..133737 (+) 435 WP_222337406.1 competence type IV pilus minor pilin ComGF Machinery gene
  K6974_RS00830 (K6974_00815) comGG 133715..134227 (+) 513 WP_222337405.1 competence type IV pilus minor pilin ComGG -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35498.35 Da        Isoelectric Point: 5.3010

>NTDB_id=599968 K6974_RS00800 WP_222337410.1 130481..131431(+) (comYA) [Streptococcus suis strain FJSM5]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNEQIDRLFAAGHISLRQAETEKIALSAPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=599968 K6974_RS00800 WP_222337410.1 130481..131431(+) (comYA) [Streptococcus suis strain FJSM5]
ATGATACAAGAAAAAGCAAGAAAGATGATTGAAGAGGCAGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGATTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCGCTTCGCTTATCAACAGTCGGCGACTATCGTGGCAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTTAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATTGAAGATCCTGTCGAGATCAAGCAGGAGGATATGCTACAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATTAAACTGTCTCTCCGTCATCGGCCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGTCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCCCGTATGTTGGAATTGGGGGTCAGCCCCGAGGAGTTAAATAATGCCCTTCAAGGCATTGCATATCAACGCTTGATCGG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTAGCGCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

69.032

98.101

0.677
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.495

99.051

0.649
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.495

99.051

0.649
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.495

99.051

0.649
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.495

99.051

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.856

99.051

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361