Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Regulator
Locus tag   KX728_RS09245 Genome accession   NZ_CP079724
Coordinates   1915067..1915819 (-) Length   250 a.a.
NCBI ID   WP_215804201.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1910067..1920819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS09225 (KX728_09220) - 1911507..1914161 (-) 2655 WP_215804203.1 YhgE/Pip domain-containing protein -
  KX728_RS09230 (KX728_09225) - 1914290..1914832 (+) 543 WP_215804202.1 TetR/AcrR family transcriptional regulator -
  KX728_RS09245 (KX728_09240) comE 1915067..1915819 (-) 753 WP_215804201.1 LytTR family DNA-binding domain-containing protein Regulator
  KX728_RS09250 (KX728_09245) comD 1915816..1917135 (-) 1320 WP_215804200.1 GHKL domain-containing protein Regulator
  KX728_RS09255 (KX728_09250) comC/comC2 1917156..1917281 (-) 126 WP_215804199.1 competence-stimulating peptide ComC Regulator
  KX728_RS09265 (KX728_09260) rlmH 1917563..1918042 (-) 480 WP_000694219.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  KX728_RS09270 (KX728_09265) htrA 1918228..1919421 (+) 1194 WP_215804198.1 S1C family serine protease Regulator
  KX728_RS09275 (KX728_09270) spo0J 1919479..1920237 (+) 759 WP_125413781.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29898.26 Da        Isoelectric Point: 6.9755

>NTDB_id=589010 KX728_RS09245 WP_215804201.1 1915067..1915819(-) (comE) [Streptococcus oralis strain 34]
MKVLILEDVIEHQVRLERILNEISEESNIPISYKTTGKVREFKEYIENDEINQLYFLDIDIHGIEKKGFEVAQFIRHHNP
YAIIVFITSRSEFATLTYKYQVSALDFVDKDINDELFKKRIEQSIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYCSHKSFLVNVGNVREIDRKNLEVVFYEDHRCPITRLKVRKL
KDILEKKSKK

Nucleotide


Download         Length: 753 bp        

>NTDB_id=589010 KX728_RS09245 WP_215804201.1 1915067..1915819(-) (comE) [Streptococcus oralis strain 34]
ATGAAAGTATTGATTTTAGAAGATGTTATTGAACATCAAGTGAGACTAGAGAGAATATTAAATGAAATCTCTGAAGAATC
GAATATTCCTATTTCATATAAGACAACAGGAAAAGTTCGTGAGTTTAAGGAATATATCGAAAATGATGAAATAAACCAGC
TTTATTTCCTAGATATCGATATTCATGGAATCGAGAAAAAAGGCTTTGAAGTGGCTCAGTTTATCCGTCATCACAATCCT
TATGCTATTATTGTCTTTATTACCAGTCGATCTGAATTTGCTACTTTAACGTACAAATACCAGGTATCAGCCCTAGATTT
TGTTGATAAAGATATCAATGATGAGTTGTTCAAAAAACGCATCGAGCAGAGTATTTTTTACACTAAGAGCATGCTGCTTG
AAAACGAAGATGTTGTAGACTATTTTGATTACAACTATAAAGGAAATGATTTGAAAATTCCTTACCATGACATTTTGTAT
ATCGAAACCACAGGAGTTTCTCATAAACTTCGGATTATTGGTAAGAATTTTGCAAAAGAATTCTATGGAACTATGACAGA
TATTCAGGAAAAGGACAAACATACCCAGCGATTTTATTGCTCCCATAAATCTTTCCTTGTCAATGTGGGAAATGTGAGAG
AAATTGATCGAAAGAATTTAGAAGTTGTCTTTTATGAAGATCATCGTTGCCCGATTACTCGTTTAAAAGTCCGCAAACTA
AAAGATATTCTAGAGAAAAAATCTAAAAAGTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-244)

Response regulator receiver domain (Response_reg)

(3-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Streptococcus mitis NCTC 12261

95.2

100

0.952
  comE Streptococcus mitis SK321

94.4

100

0.944
  comE Streptococcus pneumoniae Rx1

93.6

100

0.936
  comE Streptococcus pneumoniae D39

93.6

100

0.936
  comE Streptococcus pneumoniae R6

93.6

100

0.936
  comE Streptococcus pneumoniae TIGR4

93.6

100

0.936
  comE Streptococcus infantis strain Atu-4

93.2

100

0.932
  comE/comE2 Streptococcus gordonii strain NCTC7865

62.8

100

0.628
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

62.8

100

0.628
  comE/blpR Streptococcus mutans UA159

40.486

98.8

0.4