Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/comC2   Type   Regulator
Locus tag   KX728_RS09255 Genome accession   NZ_CP079724
Coordinates   1917156..1917281 (-) Length   41 a.a.
NCBI ID   WP_215804199.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1912156..1922281
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS09230 (KX728_09225) - 1914290..1914832 (+) 543 WP_215804202.1 TetR/AcrR family transcriptional regulator -
  KX728_RS09245 (KX728_09240) comE 1915067..1915819 (-) 753 WP_215804201.1 LytTR family DNA-binding domain-containing protein Regulator
  KX728_RS09250 (KX728_09245) comD 1915816..1917135 (-) 1320 WP_215804200.1 GHKL domain-containing protein Regulator
  KX728_RS09255 (KX728_09250) comC/comC2 1917156..1917281 (-) 126 WP_215804199.1 competence-stimulating peptide ComC Regulator
  KX728_RS09265 (KX728_09260) rlmH 1917563..1918042 (-) 480 WP_000694219.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  KX728_RS09270 (KX728_09265) htrA 1918228..1919421 (+) 1194 WP_215804198.1 S1C family serine protease Regulator
  KX728_RS09275 (KX728_09270) spo0J 1919479..1920237 (+) 759 WP_125413781.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 41 a.a.        Molecular weight: 5020.74 Da        Isoelectric Point: 8.8368

>NTDB_id=589012 KX728_RS09255 WP_215804199.1 1917156..1917281(-) (comC/comC2) [Streptococcus oralis strain 34]
MKNTEKLEQFKEVTETELQEIRGGDWRISETIRNLIFPRRK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=589012 KX728_RS09255 WP_215804199.1 1917156..1917281(-) (comC/comC2) [Streptococcus oralis strain 34]
ATGAAAAATACAGAAAAGTTGGAACAATTTAAAGAAGTAACAGAGACAGAATTGCAGGAGATTCGAGGTGGAGATTGGAG
AATTTCAGAAACAATTCGTAATCTTATTTTTCCAAGAAGAAAGTAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

53.659

100

0.537
  comC/comC2 Streptococcus pneumoniae TIGR4

53.659

100

0.537
  comC Streptococcus mitis SK321

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae R6

51.22

100

0.512
  comC/comC1 Streptococcus pneumoniae G54

51.22

100

0.512
  comC/comC1 Streptococcus pneumoniae D39

51.22

100

0.512
  comC/comC1 Streptococcus pneumoniae Rx1

51.22

100

0.512
  comC Streptococcus mitis NCTC 12261

45

97.561

0.439
  comC/comC2 Streptococcus gordonii strain NCTC7865

43.243

90.244

0.39
  comC/comC1 Streptococcus gordonii str. Challis substr. CH1

39.474

92.683

0.366