Detailed information NTG0589013

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: KX728_RS09270
• Genome accession: NZ_CP079724
• Coordinates: 1918228..1919421 (+)
• Length: 397 a.a.
• NCBI ID: WP_215804198.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain 34
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1913228..1924421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KX728_RS09230 (KX728_09225)	-	1914290..1914832 (+)	543	WP_215804202.1	TetR/AcrR family transcriptional regulator	-
KX728_RS09245 (KX728_09240)	comE	1915067..1915819 (-)	753	WP_215804201.1	LytTR family DNA-binding domain-containing protein	Regulator
KX728_RS09250 (KX728_09245)	comD	1915816..1917135 (-)	1320	WP_215804200.1	GHKL domain-containing protein	Regulator
KX728_RS09255 (KX728_09250)	comC/comC2	1917156..1917281 (-)	126	WP_215804199.1	competence-stimulating peptide ComC	Regulator
KX728_RS09265 (KX728_09260)	rlmH	1917563..1918042 (-)	480	WP_000694219.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
KX728_RS09270 (KX728_09265)	htrA	1918228..1919421 (+)	1194	WP_215804198.1	S1C family serine protease	Regulator
KX728_RS09275 (KX728_09270)	spo0J	1919479..1920237 (+)	759	WP_125413781.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 41968.82 Da
• Isoelectric Point: 6.6581

>NTDB_id=589013 KX728_RS09270 WP_215804198.1 1918228..1919421(+) (htrA) [Streptococcus oralis strain 34]
MKHLQKFYKKVVKVLVIILIGFLSGALGSFVTLQLYQKQGNQATNNNSGTVTQTSYKNENSTTQAVNKVKDAVVSIITYS
SSSRQSSVFNGDETNSDSDNQQIASEGSGVIYKKDDKDAYLVTNTHVINGASKVDIRLADGTKVPGEIVGSDTFSDIAVV
KISSEKVTTVAEFGDSSQLSVGETAIAIGSPLGSEYANTVTQGIISSLNRNVSLKSEDGQAISTKAIQTDTAINPGNSGG
PLVNIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDAQNIIKQLESNGKVTRPALGIQMVNLSNVGASDLRKLNIPSGLT
SGVVVRSVQNNMPANGHLQKYDVITKVDDKEIASSTDLQHALYNHAIGDTIKVTYYRNGKEETTSIKLDKNSSDLES

Nucleotide

• Length: 1194 bp

>NTDB_id=589013 KX728_RS09270 WP_215804198.1 1918228..1919421(+) (htrA) [Streptococcus oralis strain 34]
ATGAAACACTTACAAAAATTTTACAAAAAGGTAGTTAAAGTTCTTGTAATCATTCTAATCGGATTTTTAAGTGGTGCCTT
AGGAAGTTTCGTAACATTACAACTTTATCAAAAACAAGGAAATCAAGCTACAAATAATAATTCTGGCACTGTCACTCAAA
CATCCTATAAGAATGAAAATTCAACCACTCAAGCAGTAAATAAAGTTAAGGATGCTGTTGTCTCAATCATTACTTATTCT
TCTAGCAGTAGACAAAGCAGTGTATTTAATGGTGATGAAACTAATTCTGATTCAGACAATCAACAAATCGCGAGTGAGGG
ATCAGGTGTTATCTATAAAAAAGATGATAAAGATGCCTATCTTGTAACTAATACTCACGTTATCAATGGAGCTTCAAAAG
TTGATATTCGCTTGGCAGATGGTACCAAGGTTCCTGGTGAAATTGTCGGATCTGATACTTTCTCTGATATTGCTGTCGTT
AAAATTTCTTCAGAAAAAGTTACAACAGTGGCAGAATTTGGAGATTCAAGTCAACTTAGTGTTGGAGAAACAGCGATTGC
TATCGGTAGTCCTTTAGGTTCAGAATATGCTAATACAGTTACACAGGGGATTATTTCAAGTCTTAATCGAAATGTTTCTC
TAAAATCTGAAGATGGTCAAGCTATTTCAACAAAAGCCATTCAAACAGATACAGCCATTAACCCTGGTAACTCTGGTGGT
CCACTTGTAAATATTCAAGGACAAGTAATTGGTATTACATCAAGTAAAATTGCAAGTAATGGTGGAACATCTGTAGAAGG
TCTTGGTTTTGCAATTCCTTCAAACGATGCACAAAATATCATTAAACAGCTTGAAAGTAATGGTAAAGTGACTCGTCCAG
CTCTTGGAATTCAAATGGTCAATCTGTCAAATGTTGGAGCTAGTGATCTTAGAAAACTTAACATTCCAAGTGGCCTCACT
TCAGGTGTAGTTGTTCGATCTGTTCAAAACAATATGCCAGCAAATGGACACCTTCAAAAATACGATGTCATTACCAAAGT
TGACGACAAAGAGATTGCCTCATCAACAGACCTACAACATGCTCTTTACAATCATGCTATTGGAGATACTATCAAAGTAA
CCTACTACCGTAACGGTAAGGAGGAAACAACCTCAATTAAACTAGATAAGAATTCTAGTGATTTAGAGTCTTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (107-252)

• Peptidase family M50 (Peptidase_M50) (48-392)

• PDZ domain (PDZ_2) (293-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	83.627	100	0.836
htrA	Streptococcus pneumoniae Rx1	83.123	100	0.831
htrA	Streptococcus pneumoniae D39	83.123	100	0.831
htrA	Streptococcus pneumoniae R6	83.123	100	0.831
htrA	Streptococcus pneumoniae TIGR4	83.123	100	0.831
htrA	Streptococcus gordonii str. Challis substr. CH1	66.833	100	0.675
htrA	Streptococcus mutans UA159	54.75	100	0.552