Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   KX728_RS09250 Genome accession   NZ_CP079724
Coordinates   1915816..1917135 (-) Length   439 a.a.
NCBI ID   WP_215804200.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1910816..1922135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS09225 (KX728_09220) - 1911507..1914161 (-) 2655 WP_215804203.1 YhgE/Pip domain-containing protein -
  KX728_RS09230 (KX728_09225) - 1914290..1914832 (+) 543 WP_215804202.1 TetR/AcrR family transcriptional regulator -
  KX728_RS09245 (KX728_09240) comE 1915067..1915819 (-) 753 WP_215804201.1 LytTR family DNA-binding domain-containing protein Regulator
  KX728_RS09250 (KX728_09245) comD 1915816..1917135 (-) 1320 WP_215804200.1 GHKL domain-containing protein Regulator
  KX728_RS09255 (KX728_09250) comC/comC2 1917156..1917281 (-) 126 WP_215804199.1 competence-stimulating peptide ComC Regulator
  KX728_RS09265 (KX728_09260) rlmH 1917563..1918042 (-) 480 WP_000694219.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  KX728_RS09270 (KX728_09265) htrA 1918228..1919421 (+) 1194 WP_215804198.1 S1C family serine protease Regulator
  KX728_RS09275 (KX728_09270) spo0J 1919479..1920237 (+) 759 WP_125413781.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51225.24 Da        Isoelectric Point: 7.0076

>NTDB_id=589011 KX728_RS09250 WP_215804200.1 1915816..1917135(-) (comD) [Streptococcus oralis strain 34]
MDLFGLGIAIFYFLIISKSYEWICKINRKEQIVFFCYTCISVFILEEIITLVYSNSFALSKFLFPLVVYLYLRKLKKSEK
YKAIFISLLLSLLYHSTHTFISVTLSSITGDEVVLHYKSTFLLVVLLMTYLSILIIIRYFHLEIKYFDKDYLYPFLKKVI
VAFFGLHILLFISDIVSTTHHLNSFGSILSTIVFICLLLIFFAMNSHKVQIEKEIALKQKKFEQKHLQTYTDEIVELYNE
IRGFRHDYAGMLVSMQMAIDSGDLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIEDSALRSLIAQSIVYARKNDVEFTL
EVKDIITRLSIDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=589011 KX728_RS09250 WP_215804200.1 1915816..1917135(-) (comD) [Streptococcus oralis strain 34]
ATGGATTTATTTGGATTAGGGATAGCTATTTTTTATTTTCTCATCATTAGTAAAAGTTATGAATGGATTTGTAAAATCAA
TAGAAAAGAACAAATTGTTTTTTTCTGTTACACATGTATCTCAGTTTTTATACTTGAAGAAATTATTACACTAGTATATT
CTAATAGTTTTGCTTTGTCTAAATTTTTATTTCCTTTGGTTGTGTACCTTTATTTAAGAAAGTTAAAGAAGTCTGAAAAA
TACAAAGCTATTTTTATCAGTTTACTATTGTCTTTATTATATCACAGTACTCATACTTTTATATCCGTAACCTTATCTTC
TATAACAGGAGATGAAGTAGTATTACACTATAAAAGTACATTTCTTTTAGTAGTATTGTTGATGACTTATTTATCTATTC
TAATAATAATTCGTTATTTTCATCTGGAAATTAAATATTTTGATAAAGATTATCTGTACCCTTTTTTAAAAAAAGTAATA
GTTGCTTTCTTTGGTTTGCATATCTTATTATTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTCACAAGGTTCAAATTGAAAAAG
AGATTGCTCTAAAACAAAAGAAATTTGAACAAAAACATTTACAGACTTATACTGATGAAATTGTGGAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCCGGGATGCTTGTCAGCATGCAAATGGCGATTGATAGTGGAGATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTCTTAGTAAAAGCAAATCAGAAATTGAGGTCAGAAAAATATACTTACTTTGATTTAAATA
ATATAGAAGATTCTGCTTTACGAAGTTTAATTGCTCAATCTATTGTCTATGCACGAAAAAATGATGTAGAGTTTACATTG
GAAGTAAAGGATATCATTACTAGACTGTCAATAGATTTACTTGATCTTGTTCGTATCATGAGCATTTTATTAAATAATGC
CGTTGAAGGTGCTGCAGATAGTTACTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAAACAGTTATAGTTA
TCCAGAATTCATGCAAAATCACTATGACGCCTTCAGAGGATCTATTTGCCTTAGGTTTCTCTACCAAGGGAAGAAATAGA
GGTTTAGGACTCAATAATGTCAAAGAGATTTTAGATAAGTATGACAACATTATCTTAGAAACTGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

75.057

100

0.754
  comD Streptococcus mitis NCTC 12261

74.83

100

0.752
  comD/comD2 Streptococcus pneumoniae TIGR4

74.603

100

0.749
  comD/comD1 Streptococcus pneumoniae D39

74.15

100

0.745
  comD/comD1 Streptococcus pneumoniae R6

74.15

100

0.745
  comD/comD1 Streptococcus pneumoniae Rx1

74.15

100

0.745
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.465

85.194

0.421
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.936

85.649

0.419