Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   SPN034156_RS04970 Genome accession   NC_021006
Coordinates   908084..909025 (-) Length   313 a.a.
NCBI ID   WP_000249552.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN034156     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 903084..914025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN034156_RS04925 (SPN034156_08820) comYH 903570..904523 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  SPN034156_RS11320 (SPN034156_08830) - 904584..905178 (-) 595 Protein_911 methyltransferase domain-containing protein -
  SPN034156_RS04940 (SPN034156_08840) comGG/cglG 905315..905728 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPN034156_RS04945 (SPN034156_08850) comGF/cglF 905706..906167 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPN034156_RS04950 (SPN034156_08860) comGE/cglE 906130..906432 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPN034156_RS04955 (SPN034156_08870) comGD/cglD 906395..906799 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPN034156_RS04960 (SPN034156_08880) comGC/cglC 906792..907118 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  SPN034156_RS04965 (SPN034156_08890) comGB/cglB 907120..908136 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPN034156_RS04970 (SPN034156_08900) comGA/cglA/cilD 908084..909025 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  SPN034156_RS04975 (SPN034156_08910) - 909101..909466 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPN034156_RS04980 (SPN034156_08920) - 909617..910675 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  SPN034156_RS04985 (SPN034156_08930) nagA 910838..911989 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  SPN034156_RS04990 (SPN034156_08940) - 912142..913959 (-) 1818 WP_001220922.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35587.57 Da        Isoelectric Point: 6.0083

>NTDB_id=58031 SPN034156_RS04970 WP_000249552.1 908084..909025(-) (comGA/cglA/cilD) [Streptococcus pneumoniae SPN034156]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=58031 SPN034156_RS04970 WP_000249552.1 908084..909025(-) (comGA/cglA/cilD) [Streptococcus pneumoniae SPN034156]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGCTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCCAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGTCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACATCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.403

100

0.984
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.805

100

0.968
  comYA Streptococcus gordonii str. Challis substr. CH1

77.742

99.042

0.77
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.912

86.901

0.364

Multiple sequence alignment