Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   I6L85_RS01255 Genome accession   NZ_CP077248
Coordinates   229377..230315 (+) Length   312 a.a.
NCBI ID   WP_111724182.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 224377..235315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS01245 (I6L85_01245) rpoC 225008..228655 (+) 3648 WP_008810066.1 DNA-directed RNA polymerase subunit beta' -
  I6L85_RS01250 (I6L85_01250) - 228906..229274 (+) 369 WP_046164737.1 DUF1033 family protein -
  I6L85_RS01255 (I6L85_01255) comYA 229377..230315 (+) 939 WP_111724182.1 competence type IV pilus ATPase ComGA Machinery gene
  I6L85_RS01260 (I6L85_01260) comYB 230248..231282 (+) 1035 WP_111724181.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6L85_RS01265 (I6L85_01265) comYC 231279..231596 (+) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  I6L85_RS01270 (I6L85_01270) comYD 231556..231984 (+) 429 WP_012130939.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6L85_RS01275 (I6L85_01275) comGE/cglE 231956..232249 (+) 294 WP_111724180.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6L85_RS01280 (I6L85_01280) comGF/cglF 232233..232670 (+) 438 WP_111724179.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6L85_RS01285 (I6L85_01285) comGG 232651..233082 (+) 432 WP_231872498.1 competence type IV pilus minor pilin ComGG -
  I6L85_RS01290 (I6L85_01290) comYH 233113..234066 (+) 954 WP_111724178.1 class I SAM-dependent methyltransferase Machinery gene
  I6L85_RS01295 (I6L85_01295) - 234116..235306 (+) 1191 WP_045634156.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35771.69 Da        Isoelectric Point: 5.0503

>NTDB_id=580241 I6L85_RS01255 WP_111724182.1 229377..230315(+) (comYA) [Streptococcus gordonii strain FDAARGOS 1455]
MVQKIAQAIVRQAKEESAQDIYFVPKDDCYELYMRIGDERRFIQTYDFDQLAAVISHFKFLAGMNVGEKRRSQLGSCDYR
YDDKETSIRLSTVGDYRGYESLVIRLLHDEETELKFWFTHFPELREKFKDRGLYLFSGPVGSGKTTLMHQLAQLKFKGQQ
VMSIEDPVEIKQEDMLQLQLNETIGLTYESLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIPGVY
ERLLELGVSEEELKIVLQGICYQRLIGGGGVIDFASDDYQEHEPTIWNQQIDQLLAAGHINPEQAEAEKIRN

Nucleotide


Download         Length: 939 bp        

>NTDB_id=580241 I6L85_RS01255 WP_111724182.1 229377..230315(+) (comYA) [Streptococcus gordonii strain FDAARGOS 1455]
ATGGTTCAAAAAATTGCTCAGGCGATTGTCCGGCAAGCTAAGGAAGAGTCTGCTCAGGATATTTATTTTGTACCCAAGGA
TGATTGTTATGAACTTTATATGCGGATTGGCGATGAGCGACGCTTTATACAAACTTATGATTTTGACCAATTAGCTGCTG
TAATTAGTCATTTTAAATTTTTAGCTGGGATGAATGTAGGAGAAAAACGTCGCAGTCAGCTGGGGTCCTGTGATTATCGC
TATGATGATAAGGAAACGTCAATTCGTCTGTCGACAGTAGGCGATTATCGTGGTTATGAAAGTTTGGTCATTCGACTTTT
GCACGATGAAGAGACAGAATTGAAGTTTTGGTTTACTCATTTTCCTGAATTGAGAGAGAAGTTTAAGGACCGAGGACTGT
ATCTTTTTTCGGGACCAGTAGGGAGTGGCAAGACCACTCTCATGCATCAATTAGCTCAGCTAAAATTTAAGGGTCAGCAG
GTCATGTCCATTGAGGATCCTGTTGAAATCAAGCAAGAGGATATGCTTCAGCTACAGCTGAATGAAACGATTGGTCTGAC
CTATGAAAGTCTAATTAAACTTTCCCTGCGTCACCGTCCGGACTTGCTCATCATTGGAGAAATTCGGGATAGTGAAACCG
CTAGAGCAGTAGTTCGAGCTAGCTTGACGGGAGCTACAGTTTTTTCAACGATTCATGCTAAAAGCATTCCTGGTGTTTAC
GAACGCTTATTGGAATTGGGTGTCAGCGAAGAAGAGCTAAAAATTGTTTTACAGGGTATATGCTACCAGCGCTTGATTGG
GGGAGGAGGTGTGATAGACTTTGCCAGCGACGACTACCAAGAACACGAGCCGACCATCTGGAATCAGCAGATTGATCAAC
TTCTTGCAGCAGGACATATCAATCCTGAGCAAGCAGAAGCAGAAAAAATTAGGAACTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

98.718

100

0.987
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

78.71

99.359

0.782
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

78.387

99.359

0.779
  comGA/cglA/cilD Streptococcus pneumoniae D39

78.387

99.359

0.779
  comGA/cglA/cilD Streptococcus pneumoniae R6

78.387

99.359

0.779
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

78.387

99.359

0.779
  comYA Streptococcus mutans UA159

67.412

100

0.676
  comYA Streptococcus mutans UA140

67.412

100

0.676
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.705

100

0.657
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.679

0.542