Detailed information NTG0580246

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: I6L85_RS01280
• Genome accession: NZ_CP077248
• Coordinates: 232233..232670 (+)
• Length: 145 a.a.
• NCBI ID: WP_111724179.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS 1455
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 227233..237670

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L85_RS01250 (I6L85_01250)	-	228906..229274 (+)	369	WP_046164737.1	DUF1033 family protein	-
I6L85_RS01255 (I6L85_01255)	comYA	229377..230315 (+)	939	WP_111724182.1	competence type IV pilus ATPase ComGA	Machinery gene
I6L85_RS01260 (I6L85_01260)	comYB	230248..231282 (+)	1035	WP_111724181.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6L85_RS01265 (I6L85_01265)	comYC	231279..231596 (+)	318	WP_012130940.1	competence type IV pilus major pilin ComGC	Machinery gene
I6L85_RS01270 (I6L85_01270)	comYD	231556..231984 (+)	429	WP_012130939.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6L85_RS01275 (I6L85_01275)	comGE/cglE	231956..232249 (+)	294	WP_111724180.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6L85_RS01280 (I6L85_01280)	comGF/cglF	232233..232670 (+)	438	WP_111724179.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6L85_RS01285 (I6L85_01285)	comGG	232651..233082 (+)	432	WP_231872498.1	competence type IV pilus minor pilin ComGG	-
I6L85_RS01290 (I6L85_01290)	comYH	233113..234066 (+)	954	WP_111724178.1	class I SAM-dependent methyltransferase	Machinery gene
I6L85_RS01295 (I6L85_01295)	-	234116..235306 (+)	1191	WP_045634156.1	acetate kinase	-
I6L85_RS01300 (I6L85_01300)	-	235352..236017 (+)	666	WP_111724177.1	CPBP family intramembrane glutamic endopeptidase	-
I6L85_RS01305 (I6L85_01305)	folP	236094..237059 (+)	966	WP_111724176.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16634.14 Da
• Isoelectric Point: 6.8839

>NTDB_id=580246 I6L85_RS01280 WP_111724179.1 232233..232670(+) (comGF/cglF) [Streptococcus gordonii strain FDAARGOS 1455]
MLKKGKLAAFTLLEALVALLVISGGLLVFQAMTKLLASEIQYQEQTKAKEWLLFADQLDAELSRSHFEKVEQNKLYVKQD
GKSIAFGKSRSDDFRKTDANGRGYQPMIYGLEAAQIHKEGQIVHLLLQFRDGLEREYIYRVEEEH

Nucleotide

• Length: 438 bp

>NTDB_id=580246 I6L85_RS01280 WP_111724179.1 232233..232670(+) (comGF/cglF) [Streptococcus gordonii strain FDAARGOS 1455]
ATGTTGAAAAAAGGTAAACTAGCAGCCTTTACCCTGCTAGAAGCCTTAGTGGCCCTCTTGGTCATCAGTGGTGGCCTCTT
GGTTTTCCAGGCAATGACCAAGCTTCTAGCCAGTGAGATTCAGTATCAAGAGCAAACTAAGGCCAAGGAATGGCTCTTGT
TTGCGGACCAGTTAGATGCAGAATTATCCCGGAGCCATTTTGAAAAAGTCGAGCAAAATAAGCTTTATGTCAAACAAGAT
GGCAAGTCGATTGCATTTGGTAAGTCTAGAAGCGATGATTTTAGAAAAACAGATGCGAATGGCCGTGGTTATCAGCCCAT
GATTTATGGACTAGAAGCTGCTCAAATACATAAAGAAGGTCAGATAGTTCATTTGCTTCTGCAGTTTAGAGATGGCCTAG
AAAGAGAGTACATCTATCGTGTTGAAGAAGAACATTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	67.376	97.241	0.655
comGF/cglF	Streptococcus pneumoniae Rx1	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae D39	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae R6	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae TIGR4	66.197	97.931	0.648
comGF/cglF	Streptococcus mitis SK321	65.248	97.241	0.634
comYF	Streptococcus mutans UA140	47.183	97.931	0.462
comYF	Streptococcus mutans UA159	46.479	97.931	0.455
comGF	Lactococcus lactis subsp. cremoris KW2	42.857	96.552	0.414