Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYD   Type   Machinery gene
Locus tag   I6L85_RS01270 Genome accession   NZ_CP077248
Coordinates   231556..231984 (+) Length   142 a.a.
NCBI ID   WP_012130939.1    Uniprot ID   A8AZH7
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 226556..236984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS01250 (I6L85_01250) - 228906..229274 (+) 369 WP_046164737.1 DUF1033 family protein -
  I6L85_RS01255 (I6L85_01255) comYA 229377..230315 (+) 939 WP_111724182.1 competence type IV pilus ATPase ComGA Machinery gene
  I6L85_RS01260 (I6L85_01260) comYB 230248..231282 (+) 1035 WP_111724181.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6L85_RS01265 (I6L85_01265) comYC 231279..231596 (+) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  I6L85_RS01270 (I6L85_01270) comYD 231556..231984 (+) 429 WP_012130939.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6L85_RS01275 (I6L85_01275) comGE/cglE 231956..232249 (+) 294 WP_111724180.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6L85_RS01280 (I6L85_01280) comGF/cglF 232233..232670 (+) 438 WP_111724179.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6L85_RS01285 (I6L85_01285) comGG 232651..233082 (+) 432 WP_231872498.1 competence type IV pilus minor pilin ComGG -
  I6L85_RS01290 (I6L85_01290) comYH 233113..234066 (+) 954 WP_111724178.1 class I SAM-dependent methyltransferase Machinery gene
  I6L85_RS01295 (I6L85_01295) - 234116..235306 (+) 1191 WP_045634156.1 acetate kinase -
  I6L85_RS01300 (I6L85_01300) - 235352..236017 (+) 666 WP_111724177.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16043.65 Da        Isoelectric Point: 10.1975

>NTDB_id=580244 I6L85_RS01270 WP_012130939.1 231556..231984(+) (comYD) [Streptococcus gordonii strain FDAARGOS 1455]
MVRTIVRLRQLPIKAFTVLESLLVLMISSFILLALSSSVQATFEQIQAKIFFLEFEHFYQESQKLSVSSQRKLVLEISSQ
EISNGYARLPIPKGIQAPESTQIYFDKAGGNSSLSKVQFQTKEGLVTYQLYIGNGKFKKTTN

Nucleotide


Download         Length: 429 bp        

>NTDB_id=580244 I6L85_RS01270 WP_012130939.1 231556..231984(+) (comYD) [Streptococcus gordonii strain FDAARGOS 1455]
ATGGTAAGAACAATAGTGAGACTCAGGCAGTTGCCAATTAAGGCCTTTACAGTTTTGGAAAGCCTCTTGGTCTTGATGAT
TAGCAGTTTTATCTTGCTGGCTCTATCAAGTTCAGTTCAAGCTACATTTGAACAGATTCAGGCAAAGATCTTCTTTTTAG
AATTTGAGCATTTTTATCAGGAAAGTCAGAAGCTTAGCGTATCTTCTCAGAGAAAGCTAGTGCTAGAAATATCTAGTCAA
GAGATTTCAAACGGTTATGCTCGTCTTCCAATTCCCAAAGGAATCCAAGCGCCTGAATCTACACAGATCTATTTTGATAA
GGCTGGTGGTAATTCTTCACTCAGTAAAGTTCAGTTTCAAACCAAGGAAGGACTGGTGACCTATCAACTCTATATTGGAA
ATGGCAAATTTAAGAAAACGACAAATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AZH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYD Streptococcus gordonii str. Challis substr. CH1

100

100

1
  comGD/cglD Streptococcus pneumoniae TIGR4

59.055

89.437

0.528
  comGD/cglD Streptococcus mitis SK321

59.055

89.437

0.528
  comGD/cglD Streptococcus pneumoniae Rx1

59.055

89.437

0.528
  comGD/cglD Streptococcus pneumoniae D39

59.055

89.437

0.528
  comGD/cglD Streptococcus pneumoniae R6

59.055

89.437

0.528
  comGD/cglD Streptococcus mitis NCTC 12261

55.97

94.366

0.528
  comYD Streptococcus mutans UA140

50.388

90.845

0.458
  comYD Streptococcus mutans UA159

50.388

90.845

0.458
  comGD Lactococcus lactis subsp. cremoris KW2

36.879

99.296

0.366