Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   KK0981_RS09130 Genome accession   NZ_AP017971
Coordinates   1711911..1712570 (+) Length   219 a.a.
NCBI ID   WP_000565006.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain KK0981     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1706911..1717570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KK0981_RS09105 (KK0981_37790) - 1707207..1707524 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  KK0981_RS09110 (KK0981_37800) - 1707539..1708435 (-) 897 WP_000825664.1 PEP phosphonomutase -
  KK0981_RS09115 (KK0981_37810) - 1708438..1709700 (-) 1263 WP_000413347.1 PTS sugar transporter subunit IIC -
  KK0981_RS09120 (KK0981_37820) - 1709980..1711158 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  KK0981_RS09125 (KK0981_37830) - 1711434..1711841 (-) 408 WP_000155434.1 GNAT family N-acetyltransferase -
  KK0981_RS09130 (KK0981_37840) cclA/cilC 1711911..1712570 (+) 660 WP_000565006.1 prepilin peptidase Machinery gene
  KK0981_RS09135 (KK0981_37850) - 1712622..1713773 (-) 1152 WP_000481745.1 XRE family transcriptional regulator -
  KK0981_RS09140 (KK0981_37860) - 1713788..1714519 (-) 732 WP_000934017.1 hypothetical protein -
  KK0981_RS09145 - 1714700..1714849 (+) 150 Protein_1731 prepilin peptidase -
  KK0981_RS09150 (KK0981_37870) trpA 1714821..1715597 (-) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  KK0981_RS09155 (KK0981_37880) trpB 1715590..1716813 (-) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  KK0981_RS09160 (KK0981_37890) - 1716791..1717390 (-) 600 WP_000169888.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24860.02 Da        Isoelectric Point: 7.5762

>NTDB_id=57871 KK0981_RS09130 WP_000565006.1 1711911..1712570(+) (cclA/cilC) [Streptococcus pneumoniae strain KK0981]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAALTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=57871 KK0981_RS09130 WP_000565006.1 1711911..1712570(+) (cclA/cilC) [Streptococcus pneumoniae strain KK0981]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGCTTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTTCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae D39

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae R6

99.543

100

0.995
  cclA/cilC Streptococcus pneumoniae TIGR4

94.521

100

0.945
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872

Multiple sequence alignment