Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   KRG72_RS00695 Genome accession   NZ_CP076703
Coordinates   103922..104863 (+) Length   313 a.a.
NCBI ID   WP_258255452.1    Uniprot ID   -
Organism   Streptococcus equinus strain S1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98922..109863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS00685 (KRG72_00685) rpoC 99684..103325 (+) 3642 WP_258255450.1 DNA-directed RNA polymerase subunit beta' -
  KRG72_RS00690 (KRG72_00690) - 103481..103849 (+) 369 WP_258255451.1 DUF1033 family protein -
  KRG72_RS00695 (KRG72_00695) comYA 103922..104863 (+) 942 WP_258255452.1 competence type IV pilus ATPase ComGA Machinery gene
  KRG72_RS00700 (KRG72_00700) comYB 104787..105830 (+) 1044 WP_258255453.1 competence type IV pilus assembly protein ComGB Machinery gene
  KRG72_RS00705 (KRG72_00705) comGC/cglC 105830..106123 (+) 294 WP_258255454.1 competence type IV pilus major pilin ComGC Machinery gene
  KRG72_RS00710 (KRG72_00710) comYD 106107..106538 (+) 432 WP_258255455.1 competence type IV pilus minor pilin ComGD Machinery gene
  KRG72_RS00715 (KRG72_00715) comYE 106492..106785 (+) 294 WP_258255456.1 competence type IV pilus minor pilin ComGE Machinery gene
  KRG72_RS00720 (KRG72_00720) comYF 106769..107206 (+) 438 WP_133018089.1 competence type IV pilus minor pilin ComGF Machinery gene
  KRG72_RS00725 (KRG72_00725) comGG 107178..107528 (+) 351 WP_074561135.1 competence type IV pilus minor pilin ComGG -
  KRG72_RS00730 (KRG72_00730) comYH 107582..108538 (+) 957 WP_074561136.1 class I SAM-dependent methyltransferase Machinery gene
  KRG72_RS00735 (KRG72_00735) - 108592..109791 (+) 1200 WP_258255457.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35720.80 Da        Isoelectric Point: 5.3172

>NTDB_id=577433 KRG72_RS00695 WP_258255452.1 103922..104863(+) (comYA) [Streptococcus equinus strain S1]
MIQEKAKQLIKDAVEKNAQDIYIVPKKEHYEIYQRVGDERQFIQELASDEMTSVISHFKFVAGMNVGEKRRSQLGSCDYE
FAEGEEISLRLSTVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPDK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRAIIYQRLIGGGGVVDFAKGDFEQYPPTRWNEQIESLARDGHISLEEAKIEKIAF

Nucleotide


Download         Length: 942 bp        

>NTDB_id=577433 KRG72_RS00695 WP_258255452.1 103922..104863(+) (comYA) [Streptococcus equinus strain S1]
ATGATTCAGGAAAAAGCAAAGCAGCTGATCAAGGATGCTGTTGAAAAGAATGCGCAAGATATTTACATTGTTCCTAAGAA
GGAGCACTATGAAATTTATCAACGTGTTGGTGATGAACGTCAGTTTATTCAGGAGCTTGCTAGTGATGAGATGACAAGTG
TGATTAGTCACTTTAAATTTGTGGCTGGGATGAATGTTGGTGAGAAACGTCGTAGTCAGCTAGGCTCTTGTGATTATGAA
TTTGCTGAGGGTGAAGAGATTTCGCTGCGTTTATCCACTGTTGGTGATTATCGCGGGCGTGAGAGCCTGGTCATTAGACT
TCTTTATTCAGGACGTCATGATTTGCAATATTGGTTTGATGGGATGAAGAATATTTTAGAGGCGATTGATAGTCGAGGTC
TTTATCTTTTTTCCGGGCCGGTAGGGAGTGGAAAGACTACTCTCATGTATCAATTGGTTCGTGAAAAGTTCCCTGATAAG
CAGGTCATTACGATAGAAGATCCTGTTGAGATTAAGCAGGATAATATGTTGCAGCTGCAGCTTAATGATGAGATTGGCAT
GACTTATGATAATCTTATCAAGCTCTCGCTTCGTCATAGACCTGATATTTTGATTATTGGTGAGATTCGTGATAGTGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTGACAGGTGTGCTCGTCTTTTCAACCATTCATGCGAAAAGTATTCCAGGTGTT
TATGCTAGGTTATTAGAATTGGGTGTTAGTAGGCAAGAACTTGAAAATAGTTTACGAGCTATCATTTATCAGCGATTAAT
TGGTGGTGGAGGTGTTGTGGATTTTGCCAAAGGAGATTTTGAACAGTATCCCCCAACAAGGTGGAATGAGCAAATTGAAA
GCCTTGCTAGGGACGGACATATTAGCCTTGAGGAAGCAAAAATCGAAAAAATTGCCTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

71.061

99.361

0.706
  comYA Streptococcus mutans UA140

70.74

99.361

0.703
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.419

99.042

0.668
  comYA Streptococcus gordonii str. Challis substr. CH1

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.856

100

0.649
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.898

100

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.898

100

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.898

100

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.898

100

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

43.431

87.54

0.38