Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   KRG72_RS00730 Genome accession   NZ_CP076703
Coordinates   107582..108538 (+) Length   318 a.a.
NCBI ID   WP_074561136.1    Uniprot ID   A0A1H1AJR3
Organism   Streptococcus equinus strain S1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 102582..113538
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS00690 (KRG72_00690) - 103481..103849 (+) 369 WP_258255451.1 DUF1033 family protein -
  KRG72_RS00695 (KRG72_00695) comYA 103922..104863 (+) 942 WP_258255452.1 competence type IV pilus ATPase ComGA Machinery gene
  KRG72_RS00700 (KRG72_00700) comYB 104787..105830 (+) 1044 WP_258255453.1 competence type IV pilus assembly protein ComGB Machinery gene
  KRG72_RS00705 (KRG72_00705) comGC/cglC 105830..106123 (+) 294 WP_258255454.1 competence type IV pilus major pilin ComGC Machinery gene
  KRG72_RS00710 (KRG72_00710) comYD 106107..106538 (+) 432 WP_258255455.1 competence type IV pilus minor pilin ComGD Machinery gene
  KRG72_RS00715 (KRG72_00715) comYE 106492..106785 (+) 294 WP_258255456.1 competence type IV pilus minor pilin ComGE Machinery gene
  KRG72_RS00720 (KRG72_00720) comYF 106769..107206 (+) 438 WP_133018089.1 competence type IV pilus minor pilin ComGF Machinery gene
  KRG72_RS00725 (KRG72_00725) comGG 107178..107528 (+) 351 WP_074561135.1 competence type IV pilus minor pilin ComGG -
  KRG72_RS00730 (KRG72_00730) comYH 107582..108538 (+) 957 WP_074561136.1 class I SAM-dependent methyltransferase Machinery gene
  KRG72_RS00735 (KRG72_00735) - 108592..109791 (+) 1200 WP_258255457.1 acetate kinase -
  KRG72_RS00740 (KRG72_00740) - 109951..110148 (+) 198 WP_258255458.1 helix-turn-helix transcriptional regulator -
  KRG72_RS00745 (KRG72_00745) - 110164..110364 (+) 201 WP_006531740.1 hypothetical protein -
  KRG72_RS00750 (KRG72_00750) - 110365..110820 (+) 456 WP_258255459.1 ABC transporter permease -
  KRG72_RS00755 (KRG72_00755) - 110836..111471 (+) 636 WP_074965272.1 CPBP family intramembrane glutamic endopeptidase -
  KRG72_RS00760 (KRG72_00760) proC 111506..112276 (-) 771 WP_258255460.1 pyrroline-5-carboxylate reductase -
  KRG72_RS00765 (KRG72_00765) pepA 112338..113405 (-) 1068 WP_205396304.1 glutamyl aminopeptidase -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35899.97 Da        Isoelectric Point: 4.4591

>NTDB_id=577439 KRG72_RS00730 WP_074561136.1 107582..108538(+) (comYH) [Streptococcus equinus strain S1]
MNFEKIETAYGLILENIQLIENELKTHIYDALIEQNSFYLGAEGANETVAANNEKLRQLDLTKEEWRRAFQFIFIKAAQT
EALQANHQFTPDAIGFILMFLIENLTASKELDVLEIGSGTGNLAQTLLNNSSKDLNYLGIEVDDLLIDLSASIAEVMDSK
AQFIQEDAVRPQILKESDVIISDLPVGFYPNDEIAKRYKVASSEEHTYAHHLLMEQSLKYLKKDGIAVFLAPVSLLTSKQ
SDLLKAWLKDYADVIAVITLPESIFGNAANAKSIFVLKKQAEHTPETFVYPLADLQSREALTDFIEKFKKWNVENMIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=577439 KRG72_RS00730 WP_074561136.1 107582..108538(+) (comYH) [Streptococcus equinus strain S1]
ATGAATTTTGAAAAAATCGAAACAGCTTATGGGCTGATTCTAGAAAATATACAGTTAATCGAAAATGAGTTGAAAACACA
CATTTACGATGCTCTTATTGAACAAAACTCTTTTTATCTTGGTGCTGAAGGTGCCAATGAGACAGTAGCTGCTAATAATG
AAAAACTACGCCAACTTGATTTAACTAAAGAAGAATGGCGTCGTGCTTTTCAGTTTATTTTCATTAAAGCTGCTCAAACA
GAAGCACTTCAGGCAAACCACCAATTTACACCTGATGCAATTGGCTTTATCTTAATGTTCCTTATTGAGAATTTGACAGC
CTCAAAAGAACTTGATGTTTTAGAAATCGGTAGCGGAACAGGTAACCTTGCACAAACCTTGCTCAATAATTCATCTAAAG
ACTTAAATTACCTTGGAATTGAAGTTGATGATTTGTTGATTGATTTGTCAGCAAGTATTGCCGAAGTGATGGATTCTAAA
GCTCAGTTCATTCAAGAAGATGCTGTGCGCCCACAGATTCTTAAGGAAAGTGATGTCATCATCAGTGACCTTCCAGTCGG
CTTCTATCCAAATGATGAGATTGCAAAACGCTATAAAGTAGCAAGTAGTGAAGAACACACTTATGCGCATCATTTGTTGA
TGGAACAATCTCTCAAATATCTCAAAAAAGATGGTATTGCTGTCTTTTTAGCACCGGTTAGTCTTTTGACAAGTAAACAA
AGTGATTTGTTAAAGGCATGGTTGAAGGATTACGCTGATGTTATTGCGGTGATTACTTTACCAGAATCTATTTTCGGCAA
TGCGGCCAATGCTAAGTCAATTTTTGTCTTGAAGAAACAGGCTGAACATACTCCAGAAACATTTGTTTACCCGCTTGCTG
ACTTGCAAAGTCGCGAAGCTTTAACAGATTTTATTGAGAAATTTAAAAAATGGAATGTTGAAAATATGATTTTTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1H1AJR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

68.038

99.371

0.676
  comYH Streptococcus mutans UA159

67.722

99.371

0.673