Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   KRG72_RS00715 Genome accession   NZ_CP076703
Coordinates   106492..106785 (+) Length   97 a.a.
NCBI ID   WP_258255456.1    Uniprot ID   -
Organism   Streptococcus equinus strain S1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 101492..111785
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS00690 (KRG72_00690) - 103481..103849 (+) 369 WP_258255451.1 DUF1033 family protein -
  KRG72_RS00695 (KRG72_00695) comYA 103922..104863 (+) 942 WP_258255452.1 competence type IV pilus ATPase ComGA Machinery gene
  KRG72_RS00700 (KRG72_00700) comYB 104787..105830 (+) 1044 WP_258255453.1 competence type IV pilus assembly protein ComGB Machinery gene
  KRG72_RS00705 (KRG72_00705) comGC/cglC 105830..106123 (+) 294 WP_258255454.1 competence type IV pilus major pilin ComGC Machinery gene
  KRG72_RS00710 (KRG72_00710) comYD 106107..106538 (+) 432 WP_258255455.1 competence type IV pilus minor pilin ComGD Machinery gene
  KRG72_RS00715 (KRG72_00715) comYE 106492..106785 (+) 294 WP_258255456.1 competence type IV pilus minor pilin ComGE Machinery gene
  KRG72_RS00720 (KRG72_00720) comYF 106769..107206 (+) 438 WP_133018089.1 competence type IV pilus minor pilin ComGF Machinery gene
  KRG72_RS00725 (KRG72_00725) comGG 107178..107528 (+) 351 WP_074561135.1 competence type IV pilus minor pilin ComGG -
  KRG72_RS00730 (KRG72_00730) comYH 107582..108538 (+) 957 WP_074561136.1 class I SAM-dependent methyltransferase Machinery gene
  KRG72_RS00735 (KRG72_00735) - 108592..109791 (+) 1200 WP_258255457.1 acetate kinase -
  KRG72_RS00740 (KRG72_00740) - 109951..110148 (+) 198 WP_258255458.1 helix-turn-helix transcriptional regulator -
  KRG72_RS00745 (KRG72_00745) - 110164..110364 (+) 201 WP_006531740.1 hypothetical protein -
  KRG72_RS00750 (KRG72_00750) - 110365..110820 (+) 456 WP_258255459.1 ABC transporter permease -
  KRG72_RS00755 (KRG72_00755) - 110836..111471 (+) 636 WP_074965272.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10767.54 Da        Isoelectric Point: 6.8785

>NTDB_id=577437 KRG72_RS00715 WP_258255456.1 106492..106785(+) (comYE) [Streptococcus equinus strain S1]
MVTIKKQKLKAYILLEGLVALALLATITSLVLGEMDRSRTQMQESLHQQEVLNVATMAVQTGQDHLAINGVEVRMVKHDN
EISIYGGQNEVLHVTKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=577437 KRG72_RS00715 WP_258255456.1 106492..106785(+) (comYE) [Streptococcus equinus strain S1]
GTGGTAACTATAAAAAAACAGAAACTAAAAGCTTATATACTCCTTGAGGGCTTGGTAGCTCTTGCTTTATTAGCAACGAT
TACCAGTCTGGTCTTAGGAGAAATGGACCGTAGTCGCACTCAAATGCAAGAGAGTTTGCATCAGCAAGAAGTACTTAATG
TAGCGACCATGGCCGTTCAAACAGGACAAGACCATTTGGCTATTAATGGGGTTGAGGTGCGTATGGTTAAGCATGATAAT
GAGATTTCCATTTATGGTGGGCAAAACGAGGTGCTACATGTCACGAAAAATTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

51.042

98.969

0.505
  comYE Streptococcus mutans UA159

51.042

98.969

0.505
  comGE/cglE Streptococcus pneumoniae Rx1

41.304

94.845

0.392
  comGE/cglE Streptococcus pneumoniae D39

41.304

94.845

0.392
  comGE/cglE Streptococcus pneumoniae R6

41.304

94.845

0.392
  comGE/cglE Streptococcus pneumoniae TIGR4

41.304

94.845

0.392
  comGE/cglE Streptococcus mitis SK321

40.217

94.845

0.381
  comGE/cglE Streptococcus mitis NCTC 12261

40.217

94.845

0.381