Detailed information NTG0577438

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: KRG72_RS00720
• Genome accession: NZ_CP076703
• Coordinates: 106769..107206 (+)
• Length: 145 a.a.
• NCBI ID: WP_133018089.1
• Uniprot ID: A0A6G8I082
• Organism: Streptococcus equinus strain S1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 101769..112206

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRG72_RS00690 (KRG72_00690)	-	103481..103849 (+)	369	WP_258255451.1	DUF1033 family protein	-
KRG72_RS00695 (KRG72_00695)	comYA	103922..104863 (+)	942	WP_258255452.1	competence type IV pilus ATPase ComGA	Machinery gene
KRG72_RS00700 (KRG72_00700)	comYB	104787..105830 (+)	1044	WP_258255453.1	competence type IV pilus assembly protein ComGB	Machinery gene
KRG72_RS00705 (KRG72_00705)	comGC/cglC	105830..106123 (+)	294	WP_258255454.1	competence type IV pilus major pilin ComGC	Machinery gene
KRG72_RS00710 (KRG72_00710)	comYD	106107..106538 (+)	432	WP_258255455.1	competence type IV pilus minor pilin ComGD	Machinery gene
KRG72_RS00715 (KRG72_00715)	comYE	106492..106785 (+)	294	WP_258255456.1	competence type IV pilus minor pilin ComGE	Machinery gene
KRG72_RS00720 (KRG72_00720)	comYF	106769..107206 (+)	438	WP_133018089.1	competence type IV pilus minor pilin ComGF	Machinery gene
KRG72_RS00725 (KRG72_00725)	comGG	107178..107528 (+)	351	WP_074561135.1	competence type IV pilus minor pilin ComGG	-
KRG72_RS00730 (KRG72_00730)	comYH	107582..108538 (+)	957	WP_074561136.1	class I SAM-dependent methyltransferase	Machinery gene
KRG72_RS00735 (KRG72_00735)	-	108592..109791 (+)	1200	WP_258255457.1	acetate kinase	-
KRG72_RS00740 (KRG72_00740)	-	109951..110148 (+)	198	WP_258255458.1	helix-turn-helix transcriptional regulator	-
KRG72_RS00745 (KRG72_00745)	-	110164..110364 (+)	201	WP_006531740.1	hypothetical protein	-
KRG72_RS00750 (KRG72_00750)	-	110365..110820 (+)	456	WP_258255459.1	ABC transporter permease	-
KRG72_RS00755 (KRG72_00755)	-	110836..111471 (+)	636	WP_074965272.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16145.47 Da
• Isoelectric Point: 8.9678

>NTDB_id=577438 KRG72_RS00720 WP_133018089.1 106769..107206(+) (comYF) [Streptococcus equinus strain S1]
MSRKIRLRAFTLLESLVALLVISGSILVYQGLTQSISSNVHYLSANQEEKWLLFSQQLRSELAGCQLDKVADNKLYVSKG
NQQLAYGLSKADDFRKTNASGQGYQPMLFGVTSSSISQDGNKVMIKLQLGSDMERCFVYTFETTS

Nucleotide

• Length: 438 bp

>NTDB_id=577438 KRG72_RS00720 WP_133018089.1 106769..107206(+) (comYF) [Streptococcus equinus strain S1]
ATGTCACGAAAAATTAGGTTAAGAGCTTTTACCCTTTTAGAGAGCTTAGTGGCTTTGCTGGTTATTTCAGGTTCTATATT
GGTTTATCAAGGATTGACCCAAAGCATTTCAAGCAATGTCCATTATTTATCGGCGAATCAAGAGGAAAAATGGTTGCTCT
TTTCTCAGCAGCTGCGTTCTGAGCTTGCGGGTTGTCAGTTGGATAAAGTTGCTGACAACAAACTCTATGTTAGTAAAGGT
AATCAGCAATTGGCTTATGGCTTGTCTAAGGCTGATGATTTTCGAAAAACAAATGCCTCAGGTCAGGGGTATCAGCCCAT
GCTCTTTGGAGTGACGTCATCAAGCATTAGTCAGGATGGCAATAAGGTGATGATTAAATTGCAATTAGGCAGTGATATGG
AGAGATGTTTTGTTTACACTTTTGAGACGACAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-129)

3D structure

• AlphaFold DB: A0A6G8I082

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.993	95.862	0.566
comYF	Streptococcus mutans UA159	58.273	95.862	0.559
comGF	Lactococcus lactis subsp. cremoris KW2	45.39	97.241	0.441
comGF/cglF	Streptococcus pneumoniae R6	45.39	97.241	0.441
comGF/cglF	Streptococcus pneumoniae TIGR4	45.39	97.241	0.441
comGF/cglF	Streptococcus pneumoniae Rx1	45.39	97.241	0.441
comGF/cglF	Streptococcus pneumoniae D39	45.39	97.241	0.441
comGF/cglF	Streptococcus mitis NCTC 12261	43.662	97.931	0.428
comGF/cglF	Streptococcus mitis SK321	42.958	97.931	0.421