Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   KPA27_RS00715 Genome accession   NZ_CP076517
Coordinates   117809..118759 (+) Length   316 a.a.
NCBI ID   WP_105140681.1    Uniprot ID   -
Organism   Streptococcus suis strain 39565     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112809..123759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPA27_RS00705 (KPA27_00705) - 116373..116738 (+) 366 WP_024395451.1 DUF1033 family protein -
  KPA27_RS00710 (KPA27_00710) - 116773..117723 (-) 951 WP_014637311.1 S66 peptidase family protein -
  KPA27_RS00715 (KPA27_00715) comYA 117809..118759 (+) 951 WP_105140681.1 competence type IV pilus ATPase ComGA Machinery gene
  KPA27_RS00720 (KPA27_00720) comYB 118671..119708 (+) 1038 WP_238492613.1 competence type IV pilus assembly protein ComGB Machinery gene
  KPA27_RS00725 (KPA27_00725) comYC 119710..119991 (+) 282 WP_024395447.1 competence type IV pilus major pilin ComGC Machinery gene
  KPA27_RS00730 (KPA27_00730) comGD 119972..120379 (+) 408 WP_024395446.1 competence type IV pilus minor pilin ComGD -
  KPA27_RS00735 (KPA27_00735) comYE 120351..120644 (+) 294 WP_002936548.1 competence type IV pilus minor pilin ComGE Machinery gene
  KPA27_RS00740 (KPA27_00740) comGF/cglF 120631..121065 (+) 435 WP_024395445.1 competence type IV pilus minor pilin ComGF Machinery gene
  KPA27_RS00745 (KPA27_00745) comGG 121043..121453 (+) 411 WP_024395444.1 competence type IV pilus minor pilin ComGG -
  KPA27_RS00750 (KPA27_00750) comYH 121510..122463 (+) 954 WP_044776365.1 class I SAM-dependent methyltransferase Machinery gene
  KPA27_RS00755 (KPA27_00755) - 122513..123700 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35506.30 Da        Isoelectric Point: 5.4746

>NTDB_id=576097 KPA27_RS00715 WP_105140681.1 117809..118759(+) (comYA) [Streptococcus suis strain 39565]
MIQEKARKLIEEAVADRVSDIYLVPRGQDYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSANQWNEQIDRLFAAGHISLRQAETEKITLGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=576097 KPA27_RS00715 WP_105140681.1 117809..118759(+) (comYA) [Streptococcus suis strain 39565]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGTGG
TCAGGACTACCAAGTCTACCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGATTAAATGTTGGTGAAAAACGCCGTAGTCAGCAGGGTTCCTGTGATTATGAT
TATGGCAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGTAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTTAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACTATCGAGGATCCTGTCGAGATCAAGCAGGAGGATATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGGCCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACGG
CGCGGGCGGTCATCAGGGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCTCGTATGTTGGAATTGGGTGTCAGTCCTGAGGAGCTAAACAATGCCCTTCAAGGCATTGCCTATCAACGATTGATTGG
GGGAGGAGGTGTGGTAGATTTTGCAAAAGGAAATTACCAAAACCATTCCGCAAACCAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

98.418

0.646
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.484

98.101

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.943

100

0.541
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364