Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   INT76_RS06230 Genome accession   NZ_CP073084
Coordinates   1229841..1230791 (-) Length   316 a.a.
NCBI ID   WP_212569662.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1224841..1235791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS06195 (INT76_06195) comYH 1226086..1227030 (-) 945 WP_212569658.1 class I SAM-dependent methyltransferase Machinery gene
  INT76_RS06200 (INT76_06200) comGG 1227105..1227524 (-) 420 WP_212569659.1 competence type IV pilus minor pilin ComGG -
  INT76_RS06205 (INT76_06205) comYF 1227502..1227936 (-) 435 WP_212573034.1 competence type IV pilus minor pilin ComGF Machinery gene
  INT76_RS06210 (INT76_06210) comYE 1227923..1228216 (-) 294 WP_212569660.1 competence type IV pilus minor pilin ComGE Machinery gene
  INT76_RS06215 (INT76_06215) comGD/cglD 1228188..1228616 (-) 429 WP_212573035.1 competence type IV pilus minor pilin ComGD Machinery gene
  INT76_RS06220 (INT76_06220) comGC/cglC 1228576..1228890 (-) 315 WP_212569661.1 competence type IV pilus major pilin ComGC Machinery gene
  INT76_RS06225 (INT76_06225) comYB 1228892..1229929 (-) 1038 WP_282960473.1 competence type IV pilus assembly protein ComGB Machinery gene
  INT76_RS06230 (INT76_06230) comGA/cglA/cilD 1229841..1230791 (-) 951 WP_212569662.1 competence type IV pilus ATPase ComGA Machinery gene
  INT76_RS06235 (INT76_06235) - 1230879..1231847 (+) 969 WP_212569663.1 S66 peptidase family protein -
  INT76_RS06240 (INT76_06240) - 1231866..1232225 (-) 360 WP_212569664.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 36162.01 Da        Isoelectric Point: 5.8950

>NTDB_id=557850 INT76_RS06230 WP_212569662.1 1229841..1230791(-) (comGA/cglA/cilD) [Streptococcus oriscaviae strain HKU75]
MVQELAKSIIADAVDKYVTDLYLVPRAQSYELYERYDDERVFVGEYDEAEFAALISHFKFMAGMNVGEKRRSQQGSCDYD
YGKGTISLRLSTVGDYRNKESLVIRFLYEGVHDLRYWFNALEEVSQEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPKQQ
VLTIEDPVEIKQDDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDQETARAVIRASLTGATVFSTVHAKSISGVY
ARLLELGIREEELKNALQGIAYQRLIKGRGIVDYANRDYQEHSNHKWNEQIDQLLADGHIDARQAQTEKIIDFRPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=557850 INT76_RS06230 WP_212569662.1 1229841..1230791(-) (comGA/cglA/cilD) [Streptococcus oriscaviae strain HKU75]
ATGGTTCAAGAATTAGCAAAAAGTATCATCGCAGATGCGGTAGACAAATATGTGACAGACCTCTATCTGGTTCCTCGTGC
CCAATCCTATGAGTTGTACGAGCGCTATGATGATGAGCGGGTCTTTGTCGGAGAATATGATGAAGCAGAATTTGCAGCCC
TGATTAGCCATTTTAAGTTTATGGCGGGCATGAATGTCGGAGAAAAGCGCCGCAGTCAACAGGGCTCCTGCGATTACGAT
TATGGCAAGGGCACCATTTCCCTGCGACTCTCAACCGTGGGTGATTACCGCAATAAGGAAAGTTTGGTCATCCGCTTCTT
GTATGAGGGCGTTCACGACCTCCGCTACTGGTTCAACGCCTTAGAGGAGGTTTCTCAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGCCCAGTCGGCTCTGGCAAAACCACCCTCATGTATCACCTTGCCAGGCTGAAATTTCCCAAGCAACAA
GTACTGACTATCGAGGATCCTGTGGAAATCAAGCAGGACGATATGCTCCAGCTCCAGCTCAATGAAGCCATTGGGGCAAC
CTATGACAATTTGATCAAGCTATCCCTGCGGCACCGGCCTGACCTGCTCATTATCGGGGAAATCCGTGACCAAGAGACCG
CAAGGGCGGTCATTCGGGCTAGCCTGACGGGGGCCACGGTCTTCTCAACCGTCCACGCCAAGTCCATCTCAGGGGTCTAT
GCCCGCCTCTTGGAGCTGGGTATTCGTGAGGAAGAGCTGAAAAATGCCCTCCAAGGCATTGCCTACCAGCGATTGATTAA
GGGAAGGGGGATTGTCGATTATGCAAACAGGGACTACCAAGAGCACTCCAACCACAAGTGGAATGAGCAGATTGATCAGC
TTCTTGCAGACGGACATATCGATGCTCGGCAGGCGCAGACCGAAAAAATTATCGATTTTAGGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

70

98.101

0.687
  comGA/cglA/cilD Streptococcus pneumoniae D39

70

98.101

0.687
  comGA/cglA/cilD Streptococcus pneumoniae R6

70

98.101

0.687
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

70

98.101

0.687
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

69.355

98.101

0.68
  comYA Streptococcus mutans UA159

68.051

99.051

0.674
  comYA Streptococcus mutans UA140

68.051

99.051

0.674
  comYA Streptococcus gordonii str. Challis substr. CH1

67.097

98.101

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

98.734

0.611
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

98.418

0.516
  comGA Latilactobacillus sakei subsp. sakei 23K

43.956

86.392

0.38