Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   INT76_RS06225 Genome accession   NZ_CP073084
Coordinates   1228892..1229929 (-) Length   345 a.a.
NCBI ID   WP_282960473.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1223892..1234929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS06185 (INT76_06185) - 1223982..1224536 (-) 555 WP_212569656.1 folate family ECF transporter S component -
  INT76_RS06190 (INT76_06190) - 1224840..1226027 (-) 1188 WP_212569657.1 acetate kinase -
  INT76_RS06195 (INT76_06195) comYH 1226086..1227030 (-) 945 WP_212569658.1 class I SAM-dependent methyltransferase Machinery gene
  INT76_RS06200 (INT76_06200) comGG 1227105..1227524 (-) 420 WP_212569659.1 competence type IV pilus minor pilin ComGG -
  INT76_RS06205 (INT76_06205) comYF 1227502..1227936 (-) 435 WP_212573034.1 competence type IV pilus minor pilin ComGF Machinery gene
  INT76_RS06210 (INT76_06210) comYE 1227923..1228216 (-) 294 WP_212569660.1 competence type IV pilus minor pilin ComGE Machinery gene
  INT76_RS06215 (INT76_06215) comGD/cglD 1228188..1228616 (-) 429 WP_212573035.1 competence type IV pilus minor pilin ComGD Machinery gene
  INT76_RS06220 (INT76_06220) comGC/cglC 1228576..1228890 (-) 315 WP_212569661.1 competence type IV pilus major pilin ComGC Machinery gene
  INT76_RS06225 (INT76_06225) comYB 1228892..1229929 (-) 1038 WP_282960473.1 competence type IV pilus assembly protein ComGB Machinery gene
  INT76_RS06230 (INT76_06230) comGA/cglA/cilD 1229841..1230791 (-) 951 WP_212569662.1 competence type IV pilus ATPase ComGA Machinery gene
  INT76_RS06235 (INT76_06235) - 1230879..1231847 (+) 969 WP_212569663.1 S66 peptidase family protein -
  INT76_RS06240 (INT76_06240) - 1231866..1232225 (-) 360 WP_212569664.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39114.37 Da        Isoelectric Point: 9.1575

>NTDB_id=557849 INT76_RS06225 WP_282960473.1 1228892..1229929(-) (comYB) [Streptococcus oriscaviae strain HKU75]
MSRLISFLQTDISMLGRRRPKKLSILGQRKVIQLFNNLFASGFHLAEIVDFLQRSQLLAESYISLLRQGLTAGKAFSDLL
SDLSFSDTVVTQVSLAEIHGNTALSLQHIEDYLAKMAQVRKKLIEVATYPIILLAFLMTIMLGLKNYLLPQLEEGNLATT
LVNHFPQLFLGGLLLMACLSLLGLIWVRKTSKIKVVRVLSRLPFLGNFVKIYLTAYYAREWGSLIGQGLELGQIVTIMQE
QPSALFQEIGRDLGQTLTRGQSFCDQILSYPFFRRELSLIIEYGQVKSKLGAELSLYADECWEEFFSKINRAMQLIQPLV
FLFVALMIVLIYAAMLLPIYQNMEI

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=557849 INT76_RS06225 WP_282960473.1 1228892..1229929(-) (comYB) [Streptococcus oriscaviae strain HKU75]
ATGAGCAGATTGATCAGCTTCTTGCAGACGGACATATCGATGCTCGGCAGGCGCAGACCGAAAAAATTATCGATTTTAGG
CCAGCGTAAGGTCATCCAGCTCTTTAACAACCTCTTTGCCAGCGGCTTCCATCTCGCAGAAATTGTTGATTTCCTCCAGC
GCAGCCAGCTCTTGGCAGAAAGTTACATTTCCCTTTTGCGGCAAGGCCTGACGGCCGGCAAAGCTTTTTCGGACCTGCTA
TCGGATTTATCCTTTTCGGATACGGTGGTGACTCAGGTCTCTCTAGCCGAAATTCACGGCAACACAGCCCTCAGTTTACA
GCATATCGAGGATTATCTGGCCAAGATGGCCCAGGTCCGCAAGAAATTGATTGAGGTGGCTACCTATCCCATCATCCTGC
TGGCTTTTCTCATGACCATTATGCTGGGCTTGAAAAACTACCTCCTGCCCCAGTTGGAGGAGGGCAATCTCGCCACCACT
CTAGTCAACCATTTTCCACAGCTTTTCCTAGGGGGCCTCTTGCTCATGGCCTGTCTCAGCTTGCTGGGTCTGATCTGGGT
GCGTAAAACCAGCAAAATCAAGGTGGTCCGTGTCCTATCCAGGCTGCCCTTCCTTGGGAACTTTGTCAAGATTTATCTGA
CAGCCTATTATGCGCGTGAGTGGGGAAGTTTGATTGGTCAGGGCTTGGAGCTGGGGCAGATTGTGACCATCATGCAGGAG
CAACCATCCGCTCTCTTTCAGGAAATTGGCCGGGACTTGGGCCAGACCTTGACCAGGGGGCAAAGTTTTTGCGACCAGAT
TTTAAGCTATCCCTTCTTTCGCAGGGAGCTCAGCCTCATCATCGAATACGGCCAGGTCAAGTCCAAGCTGGGGGCGGAGT
TGTCCCTCTATGCGGACGAGTGCTGGGAGGAATTTTTCAGCAAAATCAACCGCGCCATGCAGCTGATTCAGCCTCTGGTT
TTCCTCTTTGTGGCTCTGATGATTGTCTTGATTTACGCAGCCATGTTGCTGCCGATTTACCAAAATATGGAGATTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.081

99.71

0.629
  comYB Streptococcus mutans UA159

58.944

98.841

0.583
  comYB Streptococcus mutans UA140

58.944

98.841

0.583
  comGB/cglB Streptococcus pneumoniae Rx1

58.806

97.101

0.571
  comGB/cglB Streptococcus pneumoniae D39

58.806

97.101

0.571
  comGB/cglB Streptococcus pneumoniae R6

58.806

97.101

0.571
  comGB/cglB Streptococcus pneumoniae TIGR4

58.806

97.101

0.571
  comGB/cglB Streptococcus mitis SK321

58.507

97.101

0.568
  comGB/cglB Streptococcus mitis NCTC 12261

57.91

97.101

0.562
  comGB Lactococcus lactis subsp. cremoris KW2

52.226

97.681

0.51