Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L1P11_RS04005 Genome accession   NZ_CP091044
Coordinates   804291..804950 (-) Length   219 a.a.
NCBI ID   WP_001221491.1    Uniprot ID   -
Organism   Escherichia coli strain STEC346     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 799291..809950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1P11_RS03980 - 799495..800247 (-) 753 WP_000619462.1 GntR family transcriptional regulator -
  L1P11_RS03985 - 800534..801865 (+) 1332 WP_000778883.1 MFS transporter -
  L1P11_RS03990 ygiN 801909..802223 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  L1P11_RS03995 mdaB 802254..802835 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  L1P11_RS04000 qseC 802945..804294 (-) 1350 WP_000673406.1 quorum sensing histidine kinase QseC -
  L1P11_RS04005 ciaR 804291..804950 (-) 660 WP_001221491.1 quorum sensing response regulator transcription factor QseB Regulator
  L1P11_RS04010 ygiW 805102..805494 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  L1P11_RS04015 ygiV 805547..806029 (+) 483 WP_000183494.1 AraC family transcriptional regulator -
  L1P11_RS04020 mqsR 806234..806530 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  L1P11_RS04025 mqsA 806532..806927 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  L1P11_RS04030 ygiS 807060..808667 (+) 1608 WP_001324265.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6540

>NTDB_id=557849 L1P11_RS04005 WP_001221491.1 804291..804950(-) (ciaR) [Escherichia coli strain STEC346]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPDKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=557849 L1P11_RS04005 WP_001221491.1 804291..804950(-) (ciaR) [Escherichia coli strain STEC346]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGACAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365
  micA Streptococcus pneumoniae Cp1015

34.498

100

0.361