Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   L1A18_RS09360 Genome accession   NZ_CP090887
Coordinates   1822801..1823280 (-) Length   159 a.a.
NCBI ID   WP_000588873.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP7536     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1817801..1828280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A18_RS09355 (L1A18_09355) - 1821820..1822773 (+) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -
  L1A18_RS09360 (L1A18_09360) comX/comX2 1822801..1823280 (-) 480 WP_000588873.1 sigma-70 family RNA polymerase sigma factor Regulator
  L1A18_RS09365 (L1A18_09365) nusG 1823402..1823938 (-) 537 WP_000376736.1 transcription termination/antitermination protein NusG -
  L1A18_RS09370 (L1A18_09370) secE 1823993..1824169 (-) 177 WP_001210991.1 preprotein translocase subunit SecE -
  L1A18_RS09375 (L1A18_09375) rpmG 1824179..1824331 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  L1A18_RS09380 (L1A18_09380) pbp2a 1824384..1826579 (-) 2196 WP_000762621.1 penicillin-binding protein PBP2A -
  L1A18_RS09385 (L1A18_09385) - 1826666..1827541 (+) 876 WP_074017625.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19845.50 Da        Isoelectric Point: 7.3795

>NTDB_id=557004 L1A18_RS09360 WP_000588873.1 1822801..1823280(-) (comX/comX2) [Streptococcus pneumoniae strain NP7536]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRK
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=557004 L1A18_RS09360 WP_000588873.1 1822801..1823280(-) (comX/comX2) [Streptococcus pneumoniae strain NP7536]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTTTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAAA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae TIGR4

98.742

100

0.987
  comX/comX1 Streptococcus pneumoniae TIGR4

98.742

100

0.987
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

89.937

100

0.899
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

88.608

99.371

0.881
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

49.359

98.113

0.484
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

49.359

98.113

0.484
  comX/sigX Streptococcus suis D9

46.358

94.969

0.44
  comX/sigX Streptococcus suis isolate S10

46.358

94.969

0.44
  comX/sigX Streptococcus suis P1/7

46.358

94.969

0.44
  comX/sigX Streptococcus mutans UA159

45.333

94.34

0.428
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

94.34

0.377