Detailed information NTG0553361

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: J7T63_RS09040
• Genome accession: NZ_CP072442
• Coordinates: 1724378..1724704 (-)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain S24726
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1719378..1729704

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T63_RS09000	-	1719645..1719983 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
J7T63_RS09005 (J7T63_08930)	-	1720313..1720510 (-)	198	WP_014727723.1	helix-turn-helix transcriptional regulator	-
J7T63_RS09010 (J7T63_08935)	-	1720759..1721952 (-)	1194	WP_372429425.1	acetate kinase	-
J7T63_RS09015 (J7T63_08940)	comYH	1722008..1722964 (-)	957	WP_084831205.1	class I SAM-dependent methyltransferase	Machinery gene
J7T63_RS09020 (J7T63_08945)	comGG	1723009..1723326 (-)	318	WP_082309152.1	competence type IV pilus minor pilin ComGG	-
J7T63_RS09025 (J7T63_08950)	comYF	1723304..1723741 (-)	438	WP_082309153.1	competence type IV pilus minor pilin ComGF	Machinery gene
J7T63_RS09030 (J7T63_08955)	comGE	1723725..1724018 (-)	294	WP_082309154.1	competence type IV pilus minor pilin ComGE	-
J7T63_RS09035 (J7T63_08960)	comYD	1723990..1724418 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
J7T63_RS09040 (J7T63_08965)	comYC	1724378..1724704 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
J7T63_RS09045 (J7T63_08970)	comGB	1724701..1725800 (-)	1100	Protein_1725	competence type IV pilus assembly protein ComGB	-
J7T63_RS09050 (J7T63_08975)	comGA/cglA/cilD	1725682..1726623 (-)	942	WP_071417491.1	competence type IV pilus ATPase ComGA	Machinery gene
J7T63_RS09055 (J7T63_08980)	-	1726704..1727066 (-)	363	WP_014622006.1	DUF1033 family protein	-
J7T63_RS09060 (J7T63_08985)	-	1727336..1728585 (+)	1250	Protein_1728	ISL3 family transposase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=553361 J7T63_RS09040 WP_002946126.1 1724378..1724704(-) (comYC) [Streptococcus thermophilus strain S24726]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=553361 J7T63_RS09040 WP_002946126.1 1724378..1724704(-) (comYC) [Streptococcus thermophilus strain S24726]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATATAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361