Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   JZI48_RS06635 Genome accession   NZ_CP071145
Coordinates   1362474..1362959 (+) Length   161 a.a.
NCBI ID   WP_012680087.1    Uniprot ID   C0M8B7
Organism   Streptococcus equi subsp. equi strain 470_007     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1357474..1367959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZI48_RS06635 (JZI48_06635) comX/sigX/comX2/sigX2 1362474..1362959 (+) 486 WP_012680087.1 hypothetical protein Regulator
  JZI48_RS06640 (JZI48_06640) - 1363097..1363624 (+) 528 WP_012677393.1 YqeG family HAD IIIA-type phosphatase -
  JZI48_RS06645 (JZI48_06645) yqeH 1363624..1364742 (+) 1119 WP_012680086.1 ribosome biogenesis GTPase YqeH -
  JZI48_RS06650 (JZI48_06650) yhbY 1364769..1365110 (+) 342 WP_012680085.1 ribosome assembly RNA-binding protein YhbY -
  JZI48_RS06655 (JZI48_06655) - 1365194..1365826 (+) 633 WP_012677395.1 nicotinate-nucleotide adenylyltransferase -
  JZI48_RS06660 (JZI48_06660) yqeK 1365823..1366416 (+) 594 WP_012677396.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  JZI48_RS06665 (JZI48_06665) rsfS 1366418..1366771 (+) 354 WP_012680084.1 ribosome silencing factor -
  JZI48_RS06670 (JZI48_06670) - 1366901..1367644 (+) 744 WP_012680083.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 161 a.a.        Molecular weight: 19345.31 Da        Isoelectric Point: 7.3119

>NTDB_id=543184 JZI48_RS06635 WP_012680087.1 1362474..1362959(+) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. equi strain 470_007]
MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGSVGHAIPAGGLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
K

Nucleotide


Download         Length: 486 bp        

>NTDB_id=543184 JZI48_RS06635 WP_012680087.1 1362474..1362959(+) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. equi strain 470_007]
ATGACTGATGATTTAGTGAGGTTGTTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACAGCATTATTATATTCAGCT
GTGGGAGCTAGATGATTGGTTACAGGAGGGGCGGTTGATCTTGTATCGGTTATTGGTCACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTATATCGTTATTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGTCGGTAGGCCATGCGATACCAGCAGGTGGTTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCGATTGACAGAGGGTGAGCTGTCGCAGTTTCGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGTGAG
AAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0M8B7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

66.875

99.379

0.665
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

66.875

99.379

0.665
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

66.875

99.379

0.665
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

66.875

99.379

0.665
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

66.875

99.379

0.665
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

66.875

99.379

0.665
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

47.097

96.273

0.453
  comX/sigX Streptococcus mutans UA159

45.86

97.516

0.447
  comX Streptococcus sobrinus strain NIDR 6715-7

45.752

95.031

0.435
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

40.667

93.168

0.379
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

40.397

93.789

0.379
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

40.397

93.789

0.379
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.333

93.168

0.366
  comX/comX2 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae TIGR4

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae Rx1

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae D39

38.411

93.789

0.36
  comX/comX2 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/comX1 Streptococcus pneumoniae R6

38.411

93.789

0.36
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

38.667

93.168

0.36